Homestatic GS

Question 1

Where are the main locations of the receptors responsible for controlling body temperature?

Answer 1

hypothalamus in the brain

the skin

Question 2

Where is the location of temperature integrating centre?

Answer 2

prep-tic area

hypothalamus

Question 3

What are the main effectors involved in thermal regulation

Answer 3

sweat glands
vasomotor
metabolic effectors

Question 4

What adult body temperature is indicative of fever?

Answer 4

38 degrees

Question 5

What differentiates fever from other types of hyperthermia

Answer 5

hyperthermia is when the bodies heat rises past the set point due to an outside source.
Hyperpyrexia increases the set point and generates heat to achieve this.

Question 6

What is a pyrogen

Answer 6

fever inducing substances which are organised by the innate immune system

Question 7

Release of what class of molecules is caused by pyrogens in humans

Answer 7

• prostaglandin E2 (PGE2)

- proinflammatory cytokines

Question 8

Does a fever confer any advantage when fighting infection

Answer 8

Yes it provides a warning to the rest of the body that it is fighting an infection, elevated temperature also allows some immune response systems to work better