Urinary casts

Question 1

Casts

Answer 1

Tamm-horsfall mucoprotein accumulates in DCT and CT -> slough into urine

Question 2

Hyaline casts

Answer 2

Normal pt w/ concentrated urine

Question 3

RBC casts

Answer 3

Glomerular bleeding – glomerulonephritis

Question 4

WBC casts

Answer 4

Tubular interstial dz, acute pyelonephritis, proliferative glomerular nephritis

Question 5

Epithelial cell casts

Answer 5

Acute tubular necrosis, acute interstitial nephritis, glomerulonephritis

Question 6

Granular casts

Answer 6

Acute tubular necrosis – breakdown of cast -> muddy brown

Question 7

Fatty cast

Answer 7

Nephrotic sn – w/ cholesterol -> maltese cross in fluorescence

Question 8

Waxy casts

Answer 8

ESRD – very low flow states