Toxicity Antidotes Flashcards

1
Q

Acetaminophen

A

N-acetylcysteine

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2
Q

Salicylates

A

NaHCO3, dialysis

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3
Q

Amphetamines

A

ammonium chloride

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4
Q

Anticholinesterases, organophosphates

A

pralidoxine

sx: atropine

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5
Q

Antimuscarinic, anticholinergic agetns

A

physostigmine

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6
Q

digoxin, digitalis

A

K+, Mg2+
Anti-dig Fab

atropine for bradycardia

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7
Q

Iron

A

deferoxamine

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8
Q

Lead

A

Kids: dimercaprol, Calcium EDTA; less severe - succimer, penicillamine

Adults: succimer, calcium EDTA

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9
Q

Arsenic, mercury, gold

A

Dimercaprol

succimer

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10
Q

Copper, arsenic, gold

A

penicillamine

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11
Q

Cyanide

A

Hydroxocobalamine
Thiosulfate
Nitrates –> methemoglobin to bind cyanide

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12
Q

Methemoglobin

A

methylene blue

Vit C

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13
Q

Carbon monoxide

A

100% O2, hyperbaric

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14
Q

Methanol, ethylene glycol

A

fomepizole
ethanol
dialysis

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15
Q

Opioids

A

naloxone

naltrexone

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16
Q

Benzodiazepines

A

flumazenil (rapid causes seizures)

17
Q

TCAs

A

NaHCO3

18
Q

Heparin

A

protamine

19
Q

Warfarin

A

Vit K - slow

Quick: FFP

20
Q

t-PA, streptokinase, urokinase

A

aminocaproric acid

21
Q

Theophylline

A

causes tachycardia - tx b-blocker