Micro - normal flora, pneumonia, meningitis Flashcards
normal skin flora
staph epidermidis - coag - staph
- prevents growth of yeast
- -> blood –> bacteremia, endocarditis
Normal nose flora
S. epidermidis
S. aureus
site of MRSA colonization
Normal oral flora
anaerobes
Staph
strep - S. mutans - dental plaque and caries –> endocarditis post dental procedure
Normal colon flora
bacteriodes fragilis
E coli –> UTIs
Normal vaginal flora
lactobacillus - converts glucose –> lactic acid
pH about 4.5
e coli
anaerobes
staph
strep
group B strep - s. agalactiae
–> neonatal sepsis, meningitis, pneumonia
Causes of pneumonia in neonates (birth -28 days)
Grp B strep
E coli
Chlamydia trachomatis - 4-12 wks later
HSV
Causes of pneumonia in children
Viruses - RSV
S. pneumo
Mycoplasma pneumoniae
Chlamydophila pneumoniae
Causes of pneumonia in adults
S. pneumo H. influenzae Mycoplasma pneumoniae Chlamydophila pneumoniae influenza virus
Causes of pneumonia in elderly adults
S. pneumo H. flu Influenza virus S. aureus Gram - rods: Klebsiella pneumoniae
Causes of meningitis in neonates (birth - 28d)
Group B strep
E coli
Listeria monocytogenes
Causes of meningitis in infants and children
S. pneumo
N. meningitidis
H. flu type B
Viruses - most commonly enteroviruses
Causes of meningitis in adults
S. pneumo
N. meningitidis
Enteroviruses
Causes of meningitis in elderly adults
S. pneumo
Listeria monocytogenes
Gram - rods - E coli
Empiric treatment for meningitis
Cetriaxone + vancomycin +/- ampicillin (if listeria suspected)
Anthrax
Bacillus anthracis - spore-forming, gram + rod
Cutaneous anthrax: necrotic ulcer –> eschar w/ surrounding erythema and edema
Pulmonary anthrax: mediastinal LAD –> hemorrhagic mediastinitis –> bacteremia –> circulatory collapse and death
Anthrax meningitis - hemorrhagic
Management of exposure:
remove clothing, wash patient w/ soap and water
Ciprofloxacin or doxycycline
vaccination
Raxibacumab - monoclonal Ab neutralizes B. anthracis toxins - if other prophylactic agents not available