Biochem - Rate limiting enzymes Flashcards

1
Q

De novo pyrimidine synthesis rate limiting enzyme

A

Carbamoyl phosphate synthetase 2 (CPS2)

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2
Q

De novo purine synthesis rate limiting enzyme

A

Glutamine – PRPP – amido transferase

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3
Q

Glycolysis rate limiting enzyme

A

Phosphofructokinase 1

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4
Q

Gluconeogenesis rate limiting enzyme

A

Fructose 1,6 bisphophatase

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5
Q

Glycogen synthesis rate limiting enzyme

A

Glycogen synthase

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6
Q

Glycogenolysis rate limiting enzyme

A

Glycogen phophorylase

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7
Q

TCA cycle rate limiting enzyme

A

Isocitrate dehydrogenase

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8
Q

Hexose monophosphate shunt rate limiting enzyme

A

Glucose-6-phophate dehydrogenase (G6PD)

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9
Q

Cholesterol synthase rate limiting enzyme

A

HMG-CoA reductase

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10
Q

Ketogenesis rate limiting enzyme

A

HMG-CoA synthase

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11
Q

Fatty acid synthesis rate limiting enzyme

A

Acetyl-CoA carboxylase

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12
Q

Fatty acid degradation rate limiting enzyme

A

Carnithine acyltransferase I (CATI)

Aka carnithine palmitoyl transferase I

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13
Q

Heme synthesis rate limiting enzyme

A

Aminolevulinate synthase

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14
Q

Urea cycle rate limiting enzyme

A

CPS1 – carbamoyl phosphate synthase I in MT

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