Drug side effects - by sx Flashcards

1
Q

Flushing

A

Vancomycin “red man syndrome”
Niacin
Adenosine
Dihydropyridine CCB

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2
Q

Coronary vasospasm

A

Cocain
Amphetamines
Triptans - sumatriptan
Ergotamine

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3
Q

Dilated cardiomyopathy

A

Doxorubicin

Daunorubicin

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4
Q

Torsades de pointes

A
Potassium channel blockers (Class III)
Sodium channel blockers (Class IA)
Macrolide's
Haloperidol
Chloroquine
protease inhibitors - HIV tx

Tx: IV Mg2+

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5
Q

Thrombocytopenia

A

heparin (HIT)

Cimetidine

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6
Q

Agranulocytosis

A
Clozapine
Carbamazepine
Colchicine
Propylthiouracil
Methimazole
Dapsone
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7
Q

Aplastic anemia

A
Chloramphenicol
Benzene
NSAIDs
Propylthiouracil
Methimazole
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8
Q

Gray baby syndrome

A

Chloramphenicol

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9
Q

Hemolysis in G6PD deficiency

A
Isoniazid
Sulfonamides
Primaquine
Aspirin - high dose
Ibuprofen
Nitrofurantoin
Dapsone
Fava beans
Naphthalene
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10
Q

Thrombosis

A

OCP

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11
Q

Pulmonary fibrosis

A

Amiodarone
Bleomycin
Busulfan

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12
Q

Cough

A

ACEI –> bradykinin excess

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13
Q

Pseudomembranous colitis

A

Clindamycin

Amoxicillin/ampicillin

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14
Q

Hepatic necrosis

A

Halothane
Acetaminophen
Valproic acid
Amanita phalloides (mushroom toxin)

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15
Q

Hepatitis

A

Isoniazid

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16
Q

Tertiary adrenal insufficiency

A

corticosteroid withdrawal

17
Q

Gynecomastia

A
spirolactone
digoxin
estrogens
cimetidine
alcohol - chronic use
Ketoconazole
Marijuana (THC)

“STACKED”

18
Q

Hot flashes

A

tamoxifen

clomiphene

19
Q

Hypothyroidism

A

Amiodarone
Lithium
Sulfonamides

20
Q

Gout

A

Diuretics - loop and thiazide
Niacin
Cyclosporine
Pyrazinamide

21
Q

Gingival hyperplasia

A

Phenytoin

Verapamil

22
Q

Osteoporosis

A

Corticosteroids

Heparin

23
Q

Photosensitivity

A

Sulfonamides
Amiodarone
Tetracycline

“SAT” for photo

24
Q

Stevens-Johnson Syndrome

A
Carbamazepine
Lamotrigine
Allopurinol
Phenytoin
Phenobarbital
Penicillin
Ethosuximide
RASH - sx
Sulfa drugs

“CLAPPPERS”

25
Q

Drug induced lupus

A
Sulfonamides
Hydrazine
Isoniazid
Procainamide
Phenytoin

“SHIPP”

26
Q

Tendinitis/cartilage damage

A

fluoroquinolones

27
Q

Interstitial nephritis

A

NSAIDs
Furosemide
Antibiotics

28
Q

Diabetes insipidus

A

lithium

demeclocycline

29
Q

Fanconi syndrome

A

expired tetracycline

proximal tubule defect

30
Q

hemorrhagic cystitis

A

cyclophosphamide

ifosfamide

31
Q

parkinson-like syndrome

A

metoclopramide
Antipsychotics
reserpine

32
Q

Cinchonism

A

sx: dizziness w/ HA, vision changes, tinnitus

quinidine
quinine

33
Q

Seizures

A
bupropion
imipenem/cilastatin
isoniazid
tramadol
metoclopramide
benzodiazepine/alcohol withdrawal
34
Q

Tardive dyskinesia

A

antipsychotics

metoclopramide

35
Q

Disulfiram-like reaction

A

metronidazole
certain cephalosporins - Cefotetan, Cefamandole, Cefoperazone
procarbazine
first generation sulfonylureas - Tolbutamide
disulfiram

36
Q

nephrotoxicity + neurotoxicity

A

aminoglycosides
cisplatin
polymixins

37
Q

Nephrotoxicity + ototoxicity

A

aminoglycosides
vancomycin
loop diuretics
cisplatin

38
Q

Anticholinergic effects

A

atropine
TCAs
H1 blockers
low-potency neuroleptics