Drug side effects - by sx

Question 1

Flushing

Answer 1

Vancomycin “red man syndrome”
Niacin
Adenosine
Dihydropyridine CCB

Question 2

Coronary vasospasm

Answer 2

Cocain
Amphetamines
Triptans - sumatriptan
Ergotamine

Question 3

Dilated cardiomyopathy

Answer 3

Doxorubicin

Daunorubicin

Question 4

Torsades de pointes

Answer 4

Potassium channel blockers (Class III)
Sodium channel blockers (Class IA)
Macrolide's
Haloperidol
Chloroquine
protease inhibitors - HIV tx

Tx: IV Mg2+

Question 5

Thrombocytopenia

Answer 5

heparin (HIT)

Cimetidine

Question 6

Agranulocytosis

Answer 6

Clozapine
Carbamazepine
Colchicine
Propylthiouracil
Methimazole
Dapsone

Question 7

Aplastic anemia

Answer 7

Chloramphenicol
Benzene
NSAIDs
Propylthiouracil
Methimazole

Question 8

Gray baby syndrome

Answer 8

Chloramphenicol

Question 9

Hemolysis in G6PD deficiency

Answer 9

Isoniazid
Sulfonamides
Primaquine
Aspirin - high dose
Ibuprofen
Nitrofurantoin
Dapsone
Fava beans
Naphthalene

Question 10

Thrombosis

Answer 10

OCP

Question 11

Pulmonary fibrosis

Answer 11

Amiodarone
Bleomycin
Busulfan

Question 12

Cough

Answer 12

ACEI –> bradykinin excess

Question 13

Pseudomembranous colitis

Answer 13

Clindamycin

Amoxicillin/ampicillin

Question 14

Hepatic necrosis

Answer 14

Halothane
Acetaminophen
Valproic acid
Amanita phalloides (mushroom toxin)

Question 15

Hepatitis

Answer 15

Isoniazid

Question 16

Tertiary adrenal insufficiency

Answer 16

corticosteroid withdrawal

Question 17

Gynecomastia

Answer 17

spirolactone
digoxin
estrogens
cimetidine
alcohol - chronic use
Ketoconazole
Marijuana (THC)

“STACKED”

Question 18

Hot flashes

Answer 18

tamoxifen

clomiphene

Question 19

Hypothyroidism

Answer 19

Amiodarone
Lithium
Sulfonamides

Question 20

Gout

Answer 20

Diuretics - loop and thiazide
Niacin
Cyclosporine
Pyrazinamide

Question 21

Gingival hyperplasia

Answer 21

Phenytoin

Verapamil

Question 22

Osteoporosis

Answer 22

Corticosteroids

Heparin

Question 23

Photosensitivity

Answer 23

Sulfonamides
Amiodarone
Tetracycline

“SAT” for photo

Question 24

Stevens-Johnson Syndrome

Answer 24

Carbamazepine
Lamotrigine
Allopurinol
Phenytoin
Phenobarbital
Penicillin
Ethosuximide
RASH - sx
Sulfa drugs

“CLAPPPERS”

Question 25

Drug induced lupus

Answer 25

``` Sulfonamides Hydrazine Isoniazid Procainamide Phenytoin ``` "SHIPP"

Question 26

Tendinitis/cartilage damage

Answer 26

fluoroquinolones

Question 27

Interstitial nephritis

Answer 27

NSAIDs Furosemide Antibiotics

Question 28

Diabetes insipidus

Answer 28

lithium | demeclocycline

Question 29

Fanconi syndrome

Answer 29

expired tetracycline proximal tubule defect

Question 30

hemorrhagic cystitis

Answer 30

cyclophosphamide | ifosfamide

Question 31

parkinson-like syndrome

Answer 31

metoclopramide Antipsychotics reserpine

Question 32

Cinchonism

Answer 32

sx: dizziness w/ HA, vision changes, tinnitus quinidine quinine

Question 33

Seizures

Answer 33

``` bupropion imipenem/cilastatin isoniazid tramadol metoclopramide benzodiazepine/alcohol withdrawal ```

Question 34

Tardive dyskinesia

Answer 34

antipsychotics | metoclopramide

Question 35

Disulfiram-like reaction

Answer 35

metronidazole certain cephalosporins - Cefotetan, Cefamandole, Cefoperazone procarbazine first generation sulfonylureas - Tolbutamide disulfiram

Question 36

nephrotoxicity + neurotoxicity

Answer 36

aminoglycosides cisplatin polymixins

Question 37

Nephrotoxicity + ototoxicity

Answer 37

aminoglycosides vancomycin loop diuretics cisplatin

Question 38

Anticholinergic effects

Answer 38

atropine TCAs H1 blockers low-potency neuroleptics