Drug side effects - by sx Flashcards
Flushing
Vancomycin “red man syndrome”
Niacin
Adenosine
Dihydropyridine CCB
Coronary vasospasm
Cocain
Amphetamines
Triptans - sumatriptan
Ergotamine
Dilated cardiomyopathy
Doxorubicin
Daunorubicin
Torsades de pointes
Potassium channel blockers (Class III) Sodium channel blockers (Class IA) Macrolide's Haloperidol Chloroquine protease inhibitors - HIV tx
Tx: IV Mg2+
Thrombocytopenia
heparin (HIT)
Cimetidine
Agranulocytosis
Clozapine Carbamazepine Colchicine Propylthiouracil Methimazole Dapsone
Aplastic anemia
Chloramphenicol Benzene NSAIDs Propylthiouracil Methimazole
Gray baby syndrome
Chloramphenicol
Hemolysis in G6PD deficiency
Isoniazid Sulfonamides Primaquine Aspirin - high dose Ibuprofen Nitrofurantoin Dapsone Fava beans Naphthalene
Thrombosis
OCP
Pulmonary fibrosis
Amiodarone
Bleomycin
Busulfan
Cough
ACEI –> bradykinin excess
Pseudomembranous colitis
Clindamycin
Amoxicillin/ampicillin
Hepatic necrosis
Halothane
Acetaminophen
Valproic acid
Amanita phalloides (mushroom toxin)
Hepatitis
Isoniazid
Tertiary adrenal insufficiency
corticosteroid withdrawal
Gynecomastia
spirolactone digoxin estrogens cimetidine alcohol - chronic use Ketoconazole Marijuana (THC)
“STACKED”
Hot flashes
tamoxifen
clomiphene
Hypothyroidism
Amiodarone
Lithium
Sulfonamides
Gout
Diuretics - loop and thiazide
Niacin
Cyclosporine
Pyrazinamide
Gingival hyperplasia
Phenytoin
Verapamil
Osteoporosis
Corticosteroids
Heparin
Photosensitivity
Sulfonamides
Amiodarone
Tetracycline
“SAT” for photo
Stevens-Johnson Syndrome
Carbamazepine Lamotrigine Allopurinol Phenytoin Phenobarbital Penicillin Ethosuximide RASH - sx Sulfa drugs
“CLAPPPERS”
Drug induced lupus
Sulfonamides Hydrazine Isoniazid Procainamide Phenytoin
“SHIPP”
Tendinitis/cartilage damage
fluoroquinolones
Interstitial nephritis
NSAIDs
Furosemide
Antibiotics
Diabetes insipidus
lithium
demeclocycline
Fanconi syndrome
expired tetracycline
proximal tubule defect
hemorrhagic cystitis
cyclophosphamide
ifosfamide
parkinson-like syndrome
metoclopramide
Antipsychotics
reserpine
Cinchonism
sx: dizziness w/ HA, vision changes, tinnitus
quinidine
quinine
Seizures
bupropion imipenem/cilastatin isoniazid tramadol metoclopramide benzodiazepine/alcohol withdrawal
Tardive dyskinesia
antipsychotics
metoclopramide
Disulfiram-like reaction
metronidazole
certain cephalosporins - Cefotetan, Cefamandole, Cefoperazone
procarbazine
first generation sulfonylureas - Tolbutamide
disulfiram
nephrotoxicity + neurotoxicity
aminoglycosides
cisplatin
polymixins
Nephrotoxicity + ototoxicity
aminoglycosides
vancomycin
loop diuretics
cisplatin
Anticholinergic effects
atropine
TCAs
H1 blockers
low-potency neuroleptics
