Test 2: lecture 31 uvea

Question 1

uvea

Answer 1

vascular, pigmented (melanin) coat

iris, ciliary body – anterior uvea
choroid – posterior uvea

Question 2

Answer 2

major iridal circle

collarette (darker area around pupil)

Question 3

horse eye

Answer 3

corpora nigra

Question 4

sphrincter of the iris is controlled by — nerve and has a — arrangement

Answer 4

PARA, CN3

circular

will constrict pupil

Question 5

the dilator iris muscle is controlled by —, is arranged —

Answer 5

SYM, CN5

radial

will dialte pupil

Question 6

what does ciliary body do?

Answer 6

makes aqueous humor

provides nutrition to lens and inside of the cornea

Question 7

Answer 7

tapetum lucidim

choroid

Question 8

accomodation

Answer 8

ciliary muscle contract and release tension on the lens, making lens fatter

Question 9

— supplies 80% of oxygen to cat retina

Answer 9

choriocapillaris

Question 10

when does tapetum lucidem mature

Answer 10

16 weeks

Question 11

dycoria

Answer 11

misshaped pupil- usually caused by iris atrophy

Question 12

Answer 12

iris atrophy- common in > 7-8 year old dogs

dyscoria- misshaped pupil
sluggish contraction

Question 13

Answer 13

persistent pupillary membrane

common, vascular strands remain after birth, extend from the iris collarette

Question 14

persistent pupillary membranes extend from the —

Answer 14

iris collarette (darker area around the pupil)

Question 15

nevus

Answer 15

freckle of color in the iris (melanosis)

normal in dogs, probably cancer in a cat

Question 16

Answer 16

melanocytic neoplasm

melanocytoma- raised and dark

common in dogs, slow growing, locally expansive, rarely metastasize

treatment: enucleation

Question 17

cat eye

Answer 17

feline diffuse iris melanoma

can transform from melanosis into cancer

locally destructive and frequently metastasize but slow

treatment enucleate

Question 18

Answer 18

lymphoma

presumed solitary ocular lymphoma

could be metastatic from elsewhere, but it would be very advanced to get to eye

Question 19

Answer 19

ciliary body epithelial tumor
* adenoma > adenocarcinoma

Question 20

Answer 20

uveal cyst

benign but can look like melaloma if pigmented

cleared walled cysts may lead to glaucoma

Question 21

Answer 21

anterior uveitis- inflammation, cloudy, red, painful

Question 22

— prevents protein movement between plasma and the eye

Answer 22

blood-ocular barrier

blood-aqueous barrier (BAB)
blood retinal barrer (BRB)

Question 23

what happens to blood ocular barrier during inflammation

Answer 23

tight junctions between iris endothelial cells and non-pigemented ciliart body epithelium break down

allows protein to come into eye called aqueous flare

Question 24

aqueous flare

Answer 24

break down of the blood aqueous barrier that allows protein into the anterior chamber of the eye

Question 25

hypopyon

Answer 25

white cells/pus in the anterior chamber

Question 26

what can cause cloudy eye?

Answer 26

aqueous flare- protein into anterior chamber
corneal edema
hypopyon – white cells in the anterior chamber
keratic precipitates – macrophages

Question 27

anterior uvetitis is painful and can causes

Answer 27

blepharospasm (squinting)
tearing, enophthalmos (sucken eye)
iridocyclospasm

Question 28

hyphema

Answer 28

RBC in the anterior chamber

Question 29

uvetitis will do what to IOP

Answer 29

decreases

inflammation will decrease production of aqeuous humor

Question 30

what can cause uveitis

Answer 30

primary
* blunt trauma, corneal ulcer, cataract

systemic
* infectious disease, hypertension, neoplasia

immune mediated
* often not identified

Question 31

Golden Retriever Pigmentary
Uveitis (GRPU)

Answer 31

immune mediated uvetitis

diagnosis of exclusion

may be associated with thin wall cysts and can lead to glaucoma

progressive → usually results in removal of the eye

Question 32

how to treat uveitis

Answer 32

treat underlying cause if we know it

treat for inflammation and pain: prednisone, doxy, atropine

Question 33

long term uveitis can lead to

Answer 33

cataract
glaucoma- by iris sticking to cornea and blocking exit of aqueous humor out of the eye
phthhsis bulbi- eye shrinks from scarring

Question 34

4 year-old DLH Cat
* six-month history of colour change to right eye
* describe the abnormalities in the right eye?
* what are the likely causes of the iris abnormality?

Answer 34

uveitis

caused by
* primary: blunt trauma, ulcer, cataract
* systemic: infection (FeLV, FIP, FIV, crypto), HTN, cancer
* immune mediated