Test 1: lecture 11+ 12: congenital Flashcards
pressure overload in heart will cause
concentric hypertrophy
thick, smaller volume can fit
what congenital outflow tract obstruction can cause pressure overload in the heart
Pulmonic stenosis
sub-arotic stenosis
high afterload can be caused by
systemic HTN
pulmonary HTN
leads to increased pressure in LV→ concentric hypertropy
clinical signs of outflow tract obstruction in heart
weakness and fainting, arrhythmia and sudden death
reduced ventricular filling from concentric hypertrophy
what types of dogs get pulmonic stenosis
small to medium
beagle, bulldog, boxer, spaniel, bullmastiff
Pulmonic stenosis (PS) refers to a dynamic or fixed anatomic obstruction to flow from the — to the — vasculature.
right ventricle (RV)
pulmonary arterial
pulmonic stenosis is caused by
valve issue
can sometimes be subvalvular or supravalvular obstruction as well
type A pulmonic stenosis
fusion of the leaflets
type B pulmonic stenosis
hypoplastic valve annulus and thickened leaflets
english bulldogs can have — coronary malformation that leads to pulmonic stenosis
aberrant left coronary artery that encircles PA- causes narrowing
clinical signs of mild to moderate Pulmonic stenosis
no clinical signs
clinical signs of severe pulmonic stenosis
exercise intolerance
syncope
systolic murmur 4-6/6 loudest over left 3rd ICS
what kind of mumur for PS
systolic murmur
4-6/6 loudest over left 3rd ICS
physical exam of PS
murmur, pulse, membranes?
Systolic murmur 4-6/6 loudest over left 3rd ICS
* Arterial pulses: normal
* Mucous membranes: pink
* Ascites (rare)
xray of PS will show
bulge at pulmonic artery (post stenotic bulge)
reverse D: enlargement of the RV
PS will have — velocity
high: 6.5 m/s
measured with doppler
bernoulli equation will meaure pressure difference between right ventricle and pulmonary artery
pressure gradient: 4x velocity²
4 x (6.5^2)= 170 mmHg
normal velocity of blood past pulmonic valve
1-2 m/s
PS will cause increased velocity
prognosis of mild PS
mild (0-50 mmHg)= no intervention,
can treat with beta blocker to decrease HR during exercise and reduce RV hypertrophy
prognosis of moderate PS
moderate 50-85 mmHg
+/- valvuloplasty
prognosis of severe PS
> 85 mmHg
death in 1 year without intervention
balloon dilation valvuloplasty
english bulldogs and some boxers can have a anamolous — arising from a single — associated with PS
left main coronary artery
single right coronary artery
artery can rupture during valvuloplasty
breeding advice for PS
do not breed
watch siblings
— is the most common heart defect in dogs
subaortic and aortic stenosis
what breeds will get subaortic stenosis and aortic stenosis
golden, newfoundland, boxer, german shepherd, rotti, bull terrier, bloodhound
breeding of SAS
mild SAS affected parents can produce severely affected pups
Do not recommend breeding
what is subvalvular aortic stenosis
ridge below the aortic valve causes narrowing
heart has to work harder to pump, which leads to permanent long term damage
SAS severe clinical signs
exercise intolerance, syncope, sudden death
Subvavlular aortic stenosis physical exam
systolic murmur (1-6/6) loudest over left 3rd or 4th ICS, may radiate to right side and up carotid arteries
murmur appears/increases until 1 year old
femoral pulses can be weak if severe stenosis
murmur of SAS
systolic murmur (1-6/6) loudest over left 3rd or 4th ICS, may radiate to right side and up carotid arteries
can get worse until full grown (1 year old)
why will echo have bright sections with SAS
increased pressure causes increased work and increased oxygen requirement
leads to ischemia→ fibrosis which is white on echo
how to measure pressure in LV if peak flow is 5.24m/s
4 x (5.24)²
=109 mmHg
109= LV-aorta
assume aortic pressure is 120
LV= 109+120=229 mmHg
prognosis of SAS mild
<50 mmHg
good prognosis, no intervention needed
normal life span