Targets of Major Drugs of Abuse Flashcards

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1
Q

nicotine

A

nicotinic ACh receptors

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2
Q

amphetamine

A

DAT transporter substrate

VMAT2 transporter substrate

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3
Q

cocaine

A

DAT transporter antagonist

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4
Q

morphine

A

Mu opiate receptor activators

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5
Q

cannabinoids

A

CB1 and CB2 receptors activators

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6
Q

barbiturates and benzos

A

allosteric sites of GABA-A receptor

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7
Q

hallucinogens and phencyclidine

A

NMDA receptor antagonists

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8
Q

inhalants and ethanol

A

inhibit NMDA and stimulate GABA-A receptors

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