Neuro - Misc/stop forgetting Flashcards

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1
Q

syringomyelia

A
  • lesion in ventral white commisure
  • affects pain/temp
  • SUSPENDED at level of lesion
  • next: anterior horn cells affected (LMN signs)
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2
Q

Brown-Sequard Syndrome

A
  • hemisection
  • ipsilateral: position/vibration, paralysis
  • contralateral: pain/temp sensation
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3
Q

Amyotrophic lateral sclerosis (ALS)

A
  • COMBINED UMN and LMN
  • affects long tract CST (UMN) – babinski
  • affects anterior horn cells (LMN) – fasciculations
  • sensory pathways normal
  • progressive, slow
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4
Q

spinal muscular atrophy

A

ALS variant

-LMN

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5
Q

primary lateral sclerosis

A

ALS variant

  • UMN
  • steven hawking
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6
Q

bulbar ALS

A

ALS variant

-LMN cranial nerves

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7
Q

tabes dorsalis

A
  • dorsal column affected
  • loss of pain/temp in suspended areas (spreads to ventral white commisure!!)
  • loss of position/vibration sense
  • Romburg sign
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8
Q

subacute combined degeneration posterolateral sclerosis

A
  • posterior column (Romberg)
  • CST (UMN signs)
  • vit D deficiency
  • pernicious anemia
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9
Q

B12 deficiency

A

posterior column and corticospinal tracts

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10
Q

spinocerebellar degeneration (Friedrich’s ataxia)

A
  • posterior column
  • spinocerebellar tract
  • corticospinal tract
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11
Q

Guillan-Barre Syndrome

A
  • acute demyelinating syndrome
  • autoimmune
  • after viral/bacterial illness
  • motor>sensory

Tx: plasma exchange, IVIG

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12
Q

Charcot-Marie-Tooth Syndrome

A
  • chronic demyelinating myopathy

- hereditary

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13
Q

CIDP (chronic inflammatory demyelinating nueropathy)

and Tx

A

-chronic demyelinating neuropathy

Tx: steroid, IVIG, plasma exchange

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14
Q

mysasthenia gravis is associated with

A

thymoma

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15
Q

weird symptom associated with LEMS

A

dry mouth

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16
Q

LEMS is associate with what tumor

A

SCLC

17
Q

think NEUROPATHY when…

A
  • proximal weakness
  • SYMMETRIC weakness
  • normal/enlarged muscles
  • deep tendon reflex reduction parallels muscle strength
18
Q

polymyositis

A
  • same as dermatomyositis but w/o rash
  • proximal
  • elevated CK
  • correllates with malignancy
19
Q

inclusion body myositis

A
  • DISTAL hand involvement
  • elevated CK
  • does NOT respond to steroids
20
Q

drugs that can cause myopathies

A
  • steroids

- statins

21
Q

mutation associated with Beckers

A

in frame mutation

  • partially functional protein
  • less severe than duchenne’s
22
Q

mutation associated with Duchenne’s

A
  • framshift mutation
  • nonfunctional protein
  • more severe
  • shorter life
23
Q

myotonic dystrophy

A
  • autosomal dominant
  • trinucleotide repeats
  • facial, DISTAL weakness
  • temporal wasting, frontal balding
  • myotonia - delayed relaxation
24
Q

cerebellopontine angle

A
  • extrinsic compression (tumors)
  • begins with cranial nerve signs
  • –vestibular before cochlear
  • –later involvement of V and VII
  • late occurrence of long tract signs
  • -ataxia (MCP)
  • -hemiparesis (CST)
25
Q

if III, IV, and VI are involved, think __________

A

if III, IV, and VI are involved, think cavernous sinus

26
Q

basilar artery occlusion

A
  • bilateral hemiparesis (both CSTs)
  • bilateral sensory loss (ascending systems)
  • variable cranial nerve signs
  • reticular system
27
Q

lesion of PPRF

A
  • complete lateral gaze palsy
  • neither eye can look toward the side with the lesion

(PPRF cannot communicate to contralateral MLF for opposite eye to follow either)

28
Q

internuclear ophthalmoplegia

A

MLF lesion

  • PPRF can still tell ipsilateral eye to look laterally
  • contralateral MLF cannot communicate with CN III to move medial rectus to follow other eye
  • medial nystagmus
29
Q

one and a half syndrome

A

PPRF and MLF lesions

  • complete impairment of lateral gaze on side of lesion
  • –PPRF cannot move eye lateral, and cannot communicate to contralateral MLF to have other eye follow

-when trying to move eye contralateral to lesion laterally, PPRF (intact) can move that eye, but when it tries to communicate with the contralateral MLF (lesioned) it cannot and the other eye doesn’t follow

30
Q

Parkinson’s - asymmetric or symmetric??

A

asymmetric

31
Q

main 2 symptoms of huntingtons

A
  • chorea

- dementia

32
Q

schwanoma on cerebelopontine angle

A

5, 7, 8