Old Neuro Flashcards
1
Q
syringomyelia
A
- lesion in ventral white commisure
- affects pain/temp
- SUSPENDED at level of lesion
- next: anterior horn cells affected (LMN signs)
2
Q
Brown-Sequard Syndrome
A
- hemisection
- ipsilateral: position/vibration, paralysis
- contralateral: pain/temp sensation
3
Q
Amyotrophic lateral sclerosis (ALS)
A
- COMBINED UMN and LMN
- affects long tract CST (UMN) – babinski
- affects anterior horn cells (LMN) – fasciculations
- sensory pathways normal
- progressive, slow
4
Q
spinal muscular atrophy
A
ALS variant
-LMN
5
Q
primary lateral sclerosis
A
ALS variant
- UMN
- steven hawking
6
Q
bulbar ALS
A
ALS variant
-LMN cranial nerves
7
Q
tabes dorsalis
A
- dorsal column affected
- loss of pain/temp in suspended areas (spreads to ventral white commisure!!)
- loss of position/vibration sense
- Romburg sign
8
Q
subacute combined degeneration posterolateral sclerosis
A
- posterior column (Romberg)
- CST (UMN signs)
- vit D deficiency
- pernicious anemia
9
Q
B12 deficiency
A
posterior column and corticospinal tracts
10
Q
spinocerebellar degeneration (Friedrich’s ataxia)
A
- posterior column
- spinocerebellar tract
- corticospinal tract
11
Q
Guillan-Barre Syndrome
A
- acute demyelinating syndrome
- autoimmune
- after viral/bacterial illness
- motor>sensory
Tx: plasma exchange, IVIG
12
Q
Charcot-Marie-Tooth Syndrome
A
- chronic demyelinating myopathy
- hereditary
13
Q
CIDP (chronic inflammatory demyelinating nueropathy)
and Tx
A
-chronic demyelinating neuropathy
Tx: steroid, IVIG, plasma exchange
14
Q
think NEUROPATHY when…
A
- proximal weakness
- SYMMETRIC weakness
- normal/enlarged muscles
- deep tendon reflex reduction parallels muscle strength
15
Q
myotonic dystrophy
A
- autosomal dominant
- trinucleotide repeats
- facial, DISTAL weakness
- temporal wasting, frontal balding
- myotonia - delayed relaxation
