Tamsulosin Flashcards
1
Q
absorption
A
food sensitive
- should take with food
2
Q
distribution
A
majority is distributed in extracellular fluids in the body
3
Q
metabolism
A
hepatic by CYP3A4 and CYP2D6
4
Q
excretion
A
excreted in urine
5
Q
MOA
A
- alpha 1A and alpha 1D adrenoreceptor blocker
- by blocking these adrenoreceptors, prostate smooth muscle is relaxed and improves urinary flow
6
Q
indications
A
- benign prostatic hyperplasia
7
Q
adverse effects
A
- dizziness
- palpitations
- postural hypotension
8
Q
interactions
A
- sildenafil
9
Q
contraindications
A
history of postural hypotension
