Insulin Lispro Flashcards
1
Q
absorption
A
rapidly absorbed faster than regular human insulin
2
Q
metabolism
A
involved in metabolic degradation via a receptor mediated process
3
Q
MOA
A
- binds to the insulin receptor
- stimulates tyrosine kinase activity
- leading to activation of downstream signalling molecules
4
Q
indications
A
diabetes mellitus
5
Q
adverse effects
A
- oedema
- overdose causes hypoglycaemia
6
Q
interactions
A
- clarithromycin
7
Q
contraindications
A
- dose reduction may be necessary in hepatic and renal impairment
