Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

OSCE Drug formulary > Digoxin > Flashcards

Digoxin Flashcards

1
Q

absorption

A

about 80% of drug is absorbed in small intestine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

distribution

A

extensively distributed in tissues and has large volume of distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

metabolism

A

only small fraction metabolised in liver
- CYP450 system doesn’t play major role

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

excretion

A

renally, mainly as unchanged in urine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

MOA

A
  1. Cardiac glycoside
  2. works by increasing force of myocardial contraction and reducing conductivity in the AV node
  3. induces an increase in Na+
  4. which drives the influx of calcium
  5. causing increased contractility in the heart
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

indications

A
  1. maintenance for AF or flutter
  2. heart failure
  3. emergency loading dose for AF or flutter
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

adverse effects

A
  • arrhythmias
  • cardiac conduction disorder
  • cerebral impairment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

interactions

A
  • diltiazem
  • verapamil
  • furosemide
How well did you know this?
1
Not at all
2
3
4
5
Perfectly

OSCE Drug formulary (29 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions