SZ paper 2 Flashcards
prevelance of SZ
split between sz mind and reality
only 1% likely to get it
DSM and ICD diagnosis for sz
report 2 symptoms present in 1 month period
reduced social functioning
sympoms of SZ
speech poverty-quality and amount of speech reduced negative symptom
avolution-no longer motivated to do goal ordienttaed tasks negative
delusions-irrational thinking/paranoi postive
hallucainations-auditory or visual postive
type 1 sz
charcteristed by postive symptoms
addition to the person
type 2 sz
charctersied by negative symptoms
may affect normal emotions and actions
things taken away from person
chenieux et al
use d2 psychriast to diagonse 100 patients using DSM-ICD criteria
1 psychirast found 26 with DSM and 44 with ICD
2 psychriats found 13 with DSM and 24 with icd
shows inter rater reliabilti is low
DSM and ICD criteria
DSM-states 1 of the 2 symptoms must be spostive
ICD-states 2 nehavtive symtpoms must be sufficeient
genetic explantion
greater genetic simialrity, more liekly to diagnose SZ
many candidate genes
aetogilcally heterzegeous
polygenic
dopmanine hypotheis
sz may result from excess levels of neurotransmitter dopamine
dopaminergic in sub cortex
too much dopamine
dopaminergic in cortex
too little dopamine