Section 6 pituitary Anatomy Flashcards
No projections of neurons into this lobe:
anterior
What triggers the neuron synthesizing topic hormones?
Activity of hypothalamus, floods endocrine cells in anterior pituitary gland
True or False? Many neurons are needed in the hypothalamus to release hormones.
F. only a few
slice infindibulum:
cut off communication of both the portal system and the neural lobe, neurons may regenerate, project down, and regain some function, no blood supply will come back to anterior pituitary gland.
Controls of hypothalamic centers:
heat, energy, hunger, satiety, body mass, BP, HR, sweat, blood volume, intake-thirst, output-urine volume, metabolic rate, stress, growth, reproduction, lactation
True or False? Pain can act on the neurons that control the pituitary gland, i.e. hear baby cry and start lactating
T. let down reflex
Pro-opiomelanocortins (POMC):
ACTH, ADH (adrenal control)
Two subunit glycoprotieins:
TSH, LH, FSH, alpha unit is the same to all these
3 classes of hormones released from anterior pituitary gland:
glycoprotieins, pro-opiomelanocortins, large single chain proteins
Large single chain proteins:
GH, prolactin
Are PMC’s small or large?
small
ACTH is released by this cell:
corticotroph
What does the hypothalamus release to activate or inhibit the corticotroph cell?
corticotropin-Release Hormone (CRH)
how does the CRH get from the hypothalamus to the corticotrophs?
potral circulatory
ACTH affects what target?
adrenal cortex (growth and function of gland)
Inhibiting hormones of ACTH, PIMC, MSH, B-lipotropin, gammea-lippotropin, B-endorphin, N-terminal peptide:
none
Major cleavage products of POMC:
ACTH, different versions of MSHs, endorphins, and others.
Corticotroph tumor or tumor secreting lots of ATCH:
processed via POMC (pro hormone), over-secreting ACTH, MSH, and other fragments, pigmentation coloration change
High secretion of ACTH:
darker pigmentation on inside of lips, tongue, and mucosa of mouth
alpha units are all the same for:
Two subunit glycoproteins (LH, FSH, TSH)
Cell type for LH:
gonadotroph (10-15% of cells)
TSH is aka:
Thyrotropin
Release hormone for TSH:
TRH (3 amm)
Inhibiting hormone of TSH:
Somatostatin