P6 PATHOLOGY Flashcards
lining of appendix
Columnar epithelium
gender affected with acute appendicitis more
males
Differential diagnosis of acute appendicitis in females
acute salpingitis
Ectopic pregnancy
Differential diagnosis of acute appendicitis in both males & females
meckel diverticulitis
enterocolitis
mesenteric lymphadenitis
Pathogenesis of acute appendicitis
Increased luminal pressure due to luminal obstruction
luminal obstruction is due to
small stone like mass of stool / fecalith
gallstones/ tumor/ mass of worms
mass of fecalith in lumen will trigger
ischemia & inflammatory response , tissue edema & neutrophilic infiltration
Morphology features in early stages
subserosal vessels constricted
perivascular neutrophilic infiltrate
changes of normal serosa to
dull , granular appearing , erythematous surface
if the patient did not seek medical attention , he/she may face an emergency such as
Ruptured appendix & suppurative peritonitis
pain in acute appendicitis
periumbilical pain radiating to right lower quadrant
Patient might come complaining of
nausea , vomiting , low grade fever
in acute appendicitis , what are the levels of WBC
Mildly elevated
upon physical examination , you might press on a point that increases the patient’s pain . that point is known as
McBurney’s point
most common tumor of appendix
neuroendocrine / carcinoid tumor
