P5 MICROBIOLOGY

Question 1

Enterohaemorrhagic E. coli causes

Answer 1

hemorrhagic colitis , hemolytic uremic

Question 2

Enterotoxigenic E. coli causes

Answer 2

Traveler’s diarrhea

Question 3

Enteropathogenic E. coli causes

Answer 3

infant enteritis

Question 4

2nd cause of traveler’s diarrhea

Answer 4

Enteroaggregative E. coli

Question 5

Enteroinvasive E. coli causes

Answer 5

dysentery

Question 6

Diffusely adherent E. coli causes

Answer 6

watery diarrhoea

Question 7

Pathogenesis of Enterohaemorrhagic E. coli is mediated by

Answer 7

shiga toxin

Question 8

Pathogenesis of Enterotoxigenic E. coli

Answer 8

Enterotoxins

Question 9

Invasion by endocytosis is the pathogenies of

Answer 9

Enteroinvasive E. coli

Question 10

diffuse adherence fimbriae is the pathogenesis of

Answer 10

Diffusely adherent E. coli

Question 11

Pathogenesis of Enteropathogenic E. coli

Answer 11

bundle forming pili , intimin , associated protein

Question 12

plasmid associated fimbriae is the pathogenesis of

Answer 12

Enteroaggregative E. coli

Question 13

most important serotype of STEC

Answer 13

E.coli O157;H7

Question 14

STEC can grow in temperatures ranging

Answer 14

7 - 50 C

Question 15

STEC in transmitted through

Answer 15

Contaminated food/ vegetables

Question 16

STEC is similar to what organism in producing the shiga toxin

Answer 16

Shigella dysenteriae

Question 17

Diseases caused by salmonella species

Answer 17

Gastroenteritis , typhoid fever , septicemia

Question 18

Motility of salmonella species is due to

Answer 18

peritrichous flagella

Question 19

most common species causing gastroenteritis

Answer 19

Salmonella typhimurium

Question 20

Mention the 2 antigens in salmonella species

Answer 20

flagellar antigen (H)
somatic antigen (O)

Question 21

incubation period for S.typhimurium

Answer 21

12-24 hrs

Question 22

Symptoms of salmonella infection

Answer 22

Diarrhoea , vomiting , fever , abdominal pain

Question 23

what type of bacteria is salmonella ( gram -/+)

Answer 23

gram negative bacilli

Question 24

what type of bacteria is shigella (-/+)

Answer 24

gram negative bacilli

Question 25

Motility of shiqella

Answer 25

non motile

Question 26

mention the 4 species of shigella

Answer 26

Shigella flexneri
Shigella sonnei
Shigella dysenteriae Shigella boydii

Question 27

what is the critical factor for shiqella

Answer 27

invasion of the mucosal cells

Question 28

cause of enterocolitis

Answer 28

Campylobacter jejuni

Question 29

what type of bacteria is Campylobacter jejuni

Answer 29

curved gram - negative bacilli

Question 30

what environment Campylobacter jejuni needs

Answer 30

microaerophilic

Question 31

Transmission of Campylobacter jejuni

Answer 31

Consumption of contaminated food
person to person , fecal - oral

Question 32

Symptoms of infection with Campylobacter jejuni

Answer 32

bloody diarrhoea , fever , abdominal pain

Question 33

infection of Campylobacter jejuni is associated with

Answer 33

guillain barr syndrome

Question 34

pathogenesis of C.jejuni

Answer 34

1- adherence & production of enterotoxins
2- invasion of bacteria within intestinal epithelium

Question 35

Adherence is facilitated by

Answer 35

Flagella & lipopolysaccharides

Question 36

Characteristics of norovirus

Answer 36

non-enveloped
SS positive sense RNA virus

Question 37

norovirus causes

Answer 37

acute gastroenteritis

Question 38

Transmission of norovirus

Answer 38

contaminated food / water / surfaces
Direct contact with infected people

Question 39

Symptoms of norovirus infection

Answer 39

watery diarrhea
vomiting , nausea
Abdominal pain

Question 40

specimens for lab diagnosis are taken from

Answer 40

stool
vomitus

Question 41

tests done to diagnose norovirus infection

Answer 41

1-ELISA : stool antigen detection
2- reverse transcription real time PCR