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UNIT 5 GI > P5 IMMUNOLOGY > Flashcards

P5 IMMUNOLOGY Flashcards

1
Q

Immunoglobulin that has an important role in GI

A

IgA

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2
Q

deifne GALT

A

Gut associated lymphoid tissue

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3
Q

Protein present on helper T cells

A

CD4

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4
Q

protein present on cytotoxic / killer T cells

A

CD8

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5
Q

GALT is composed of what cells

A

lymphoid + myeloid cells

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6
Q

non-immune protection of intestinal mucosa

A

gastric acid
microflora
proteolytic enzymes
Physical barrier

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7
Q

limb that gathers information on antigens

A

Afferent limb

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8
Q

limb that gives a response for antigens

A

efferent limb

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9
Q

Afferent limb is located in

A

aggregated lymphoid tissue

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10
Q

efferent limb is located in

A

diffuse lymphoid tissue

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11
Q

cells of GALT are located between

A

Intestinal lumen
& serosa of intestine

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12
Q

in GALT , lymphocytes migrate from

A

Peyer’s patches

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13
Q

Through which lymph node do lymphocytes migrate

A

Through mesenteric
lymph nodes & thoracic duct

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14
Q

has the role of antigen transportation

A

M cells

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15
Q

Major function of IgA

A

Neutralises viruses , bacteria & toxins

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16
Q

IgA is referred to as

A

mucosal antiseptic paint

17
Q

in response to parasites & allergy , which immunoglobulin will give response

A

IgE

18
Q

T-cells immune response is in common in

A

Protozoal infection , AIDS
gluten enteropathy , IBD
graft versus host reaction

19
Q

Systemic hyporesponsiveness to orally ingested antigens

A

tolerance

20
Q

Immediate hypersensitivity type 1/2 mediated by cellular activity

A

Hypersensitivity

21
Q

Genetic predisposition in Crohn’s is in

A

HLA-DR1

22
Q

T -cells in Crohn’s

A

T helper 1

23
Q

Interleukin in Crohn’s

A

IL-12

24
Q

Genetic predisposition in ulcerative colitis is in

A

HLA-DR2

25
Q

T cells in ulcerative colitis

A

T helper 2

26
Q

Interleukin in ulcerative colitis

A

IL-5

UNIT 5 GI (34 decks)

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