P6 MICROBIOLOGY Flashcards
the host response to presence of microorganisms
Infection
presence of viable bacteria in blood
Bacteremia
presence & MULTIPLICATION of bacteria in blood
septicemia
Untreated Septicaemia can progress into
sepsis
most common causative microorganism in septicaemia
Staphylococci
most common cause of sepsis infection
IV catheters
other possible source of sepsis infection
through fragile membranes
Sepsis marker
Plasma procalcitonin
new definition of sepsis
Sepsis is an infection with more than 2 points of SOFA
what is SOFA
Sequential organ failure assessment
what is septic shock
Presence of sepsis
lactate more than 2 mmol/L ( acidosis )
need vasopressor therapy to increase BP
Quick SOFA criteria
resp.rate more than 22/min
altered orientation
Systolic BP less than or 100 mm Hg
life-threatening organ dysfunction caused by dysregulated host response to infection is known as
sepsis
Increased inflammatory mediators in sepsis
IL-1 & IL-6 & TNF
what T cells are produced in the anti-inflammatory-response
TH2