P6 MICROBIOLOGY Flashcards

1
Q

the host response to presence of microorganisms

A

Infection

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2
Q

presence of viable bacteria in blood

A

Bacteremia

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3
Q

presence & MULTIPLICATION of bacteria in blood

A

septicemia

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4
Q

Untreated Septicaemia can progress into

A

sepsis

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5
Q

most common causative microorganism in septicaemia

A

Staphylococci

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6
Q

most common cause of sepsis infection

A

IV catheters

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7
Q

other possible source of sepsis infection

A

through fragile membranes

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8
Q

Sepsis marker

A

Plasma procalcitonin

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9
Q

new definition of sepsis

A

Sepsis is an infection with more than 2 points of SOFA

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10
Q

what is SOFA

A

Sequential organ failure assessment

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11
Q

what is septic shock

A

Presence of sepsis
lactate more than 2 mmol/L ( acidosis )
need vasopressor therapy to increase BP

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12
Q

Quick SOFA criteria

A

resp.rate more than 22/min
altered orientation
Systolic BP less than or 100 mm Hg

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13
Q

life-threatening organ dysfunction caused by dysregulated host response to infection is known as

A

sepsis

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14
Q

Increased inflammatory mediators in sepsis

A

IL-1 & IL-6 & TNF

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15
Q

what T cells are produced in the anti-inflammatory-response

A

TH2

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16
Q

the shift from inflammatory to anti inflammatory response causes

A

apoptosis of B , T , dendritic cells