Ovarian/Uterine Path Flashcards
what is the definition of endometriosis
normal endometrial lining growing outside the cavity - causes bleeding into tissues - inflammation and fibrosis
what are the causes of endometriosis
unknown - regurgitation theory
what are the complications, diagnosis and treatment of endometriosis
ectopic pregnancy - ovarian cancer, IBD
d - laparoscopy
t - medical (combined oral pill), GnRH agonist/antagonist
surgical - TAH-BSO
what are the causes of inflammation within the uterus
pelvic inflammatory disease, TB, infection, IUCD
during inflammation of the endometrium what is the normal cell types present
high lymphocytes and plasma cells
what are endometrial polyps
sessile (flat) or polypoid (have a stalk) oestrodial dependant uterine overgrowths
what is the diagnosis and treatment of endometrial polyps
hysteroscopy
medical - progesterone / GnRH agonist
surgical - curettage
what is another name for uterine fibroids
leiomyoma
what by definition is a leimyoma
uterine fibroids
benign tumours of myometrium with oestrdiol / progesterone dependant growth
what are the risk factors of leiomyoma
genetics, nulliparity (never give birth), obesity , hypertension
what is the treatment for myeloma
coil, NSAIDS, progesterone, iron
surgical, artery embolisation or ablation
if you a woman has increased estradiol and deceased progesterone what can this lead to
endometrial hyperplasia
what is polycystic ovary syndrome
endocrine disorder causing hyperandrogegism and menstural abnormalities leading polycystic ovaries
what is the rotterdam criteria used for
polycytisc ovary syndrome
what are the two types of gonadal failure
hypergonadotropic hyopgonadism - primary gonadal failure
hypogondotrophic hypogonadism - secondary gonadal failure
what are the congenital causes of hypergonadotropic hypogonadism vs acquired
turners or klinefelters syndrome
infection, surgery, chemo, toxins affecting gonads
what is the presentation of gondal failure
amenorrhoea, delayed puberty, deacrsed sex hormones
how can you treat gondal failure
HRT
what are three origins of ovarian neoplasm
surface epithelial tumours
germ cell tumours
sex cord stromal tumours
which type of tumour is the most common ovarian neoplasm
epithelial tumours 90%
what are the three subtypes of ovarian epithelial tumour
serious (tubal)
mucinous (endocervical)
endometriod (endometrium)
which subtype of epithelial ovarian tumours is the most common
serous cystuadenocarcinoma
malignant ovarian tumour of serious subtype and cystic variant
what are these germ cells tumours dysgerminomas teratoma yolk sac tumour choriocarcinoma
tumour of oogonias - malignant but chemosesntive (immture oocyte)
teratoma - show all three germ cell layers - mature and benign
tumour of yolk sac - chemosensitve
tumour of placenta cells - often unresponsive
what are the sex cords where tumours can from
from the surface epithelium of the ovary to surround the primordial follicles - part of the ovarian stroma
what does a sex cord stromal tumour do
produce cells of the opposite sex
what is Meigs syndrome
ovarian tumour - ascites, right sided pleural effusion - sex cord stromal tumours
what type of sex cord stromal tumour occurs in juvenile and adults and produces estradiol
granulose cell tumour
what is produced during a sertoli - leydig cell tumour
androgens
what staging is used for ovarian cancer
FIGO
where would you find a Krukenberg tumour
GIT due to lymphatic spread of ovarian metastatic tumour
what is a mullein tumour
ovarian metastatic tumour
