blood emergencies Flashcards
1
Q
what is immune thrombocytopenia purpura, causes, risks, diagnosis and therapy
A
acquired thrombocytopenia = low platelet count
idiopathic or secondary to infection risk of (intracranial) haemorrhage
presence of large platelets (megakaryocytes) due to low numbers
treat with glucocorticoids and IV IG’s
2
Q
what is acquired TTP and its effect
A
acquired thrombotic thrombocytopenia purpura - Beverly reduced vWF cleaving protease ADAMs13 = accumulation of ultra large vWF molecules
3
Q
what does acquired TTP lead to
A
thrombotic microangiography - fatal if left untreated
