GIT infections 2 Flashcards

1
Q

what are the two ways to contract foodbourne gastroenteritis

A

intoxication or infection

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2
Q

what is distinctive about s aureus food intoxication

A

no fever present and little diarrhoea - nausea and vomiting

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3
Q

what are the two entertains formed by bacillus cereus food intoxication

A

heat stable emetic from - rice and starchy foods

heat labile diarrhoea from

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4
Q

what foods are clostridium perfrigens intoxication associated with

A

meat meat products

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5
Q

which toxin is given by clostridium botulinum food intoxication and what does it do

A

neurotoxin AB blocks neurotransmission = flaccid descending paralysis, blurred vision, dry mouth

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6
Q

infant botulism can be contract from which foods

A

honey spores

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7
Q

describe salmonella gastroenteritis infection

A

gram negative anaerobes
non lactose fermenters
killed by gastric acid so need high numbers - from chickens reptiles birds and humans
usually left limiting but if needed ciprofloxacin

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8
Q

describe dysnetry and another name for it

A

gram negative anaerobe
resistant to gastric acid so low numbers needed to infect - shiga toxin
(shigella)
faecal oral route - fluid and electrolyte loss
self limiting - stop any use of ammodium

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9
Q

what are the presentations of salmonella infection

A
nausea
abdominal cramps
vomiting 
diarrhoea 
fever / headache
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10
Q

what are the presentations of dysentery (shigella)

A

watery diarrhoea
bloody mucoid stool
abdominal pain

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11
Q

describe campylobacter gastroenteritis infection and treatment and symptoms

A

microairophile - negative
heat labile toxin invades epithelial cells associated with birds
self limiting and only antibiotics with severe symptoms such as high fever, bloody diarrhoea, malaise, myalgia, headache vomiting

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12
Q

describe e coli infection and associated features

A

normal gut flora - 0157:H7
produce shiva toxin
abdominal pain, haemorrhage colitis, abdominal pain
associated with cattle and meat

acquire haemolytic uraemia syndrome

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13
Q

what are 5 types of viral gastroenteritis and main features

A

rotavirus - D + V, major cause of D in young
adenovirus - young
norovirus - 1-2 day cold
astrovirus - watery diarrhoea (nursing homes)
calicivirus - shelfish

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14
Q

what is amoebic dysentery

A
entamoeba histolytica 
parasite - cyst from 
can cause extra intestinal disease 
contaminated food and water 
abdominal pain, nausea, vomiting, tenesmus, malaise 
liver abscess
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15
Q

what is cryptosporidosis

A

parasite - cryptosporidosis parvum
severe chronic diarrhoea
cysts in faeces

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16
Q

what is giardiasis

A

parasite - most common protozoan parasite infection
water contaminant - chronic releasing disease, sudden onset, flatulence, abdominal cramps - antibiotics for confirmed diagnosis = metronidazole

17
Q

describe cholera infection

A
neg rod 
01 serotype normal 
non01 = milder disease
need high infection 
rapid fluid loss from gut 
rice water stool 
hypovolumic shock, metabolic acidosis - death if untreated
18
Q

what is enteric fevers and the two types

A

salmonella typhi and salmonella paratyphi
1st week = fever headache myalgia, malaise, diarrhoea
2nd week = diarrhoea splenomegaly high fever rose spots
need immediate antibiotic treatment with azithromycin

19
Q

what is the most common cause of antibiotic associated diarrhoea and what can it lead to

A

c difficile infection produce A/B toxins - watery diarrhoea and stomach cramps
leads to fulminant colitis and pseudomembranous colitis

20
Q

describe infection by streptococcus gallolyticus

A

pos bacillus

infective endocaridits and septicaemia in elderly - associated with CRC = inflammatory response and microbial imbalance

21
Q

describe gastrointestinal TB and with treatment

A

most commonly present AS pulmonary TB
abdominal pain, weight loss anaemia, nigh sweats
confused with other diseases
people with TB without CNS involvement give isoniazid and rifampicin