Neurological (Anti-Epileptic Drugs - Levetiracetam)

Question 1

Examples of drug (Anti-Epileptic Drugs - Levetiracetam)

Answer 1

• Levetiracetam

Question 2

Mechanism of action (Anti-Epileptic Drugs - Levetiracetam)

Answer 2

• SV2A is a synaptic vesicle protein required for neurotransmitter release
• Levetiracetam blocks this and reduced neurotransmitter release
• Induces an anti-epileptic effect

Question 3

Indications (Anti-Epileptic Drugs - Levetiracetam)

Answer 3

• Epilepsy

Question 4

Side effects (Anti-Epileptic Drugs - Levetiracetam)

Answer 4

• Headache
• Fatigue
• Anxiety
• Irritability
• Drowsiness
• Constipation

Question 5

Important pharmacokinetics/pharmacodynamics (Anti-Epileptic Drugs - Levetiracetam)

Answer 5

• Rapidly and almost completely absorbed after oral administration (99%)
• Food does not affect bioavailability
• Cytochrome P450 is not involved in its metabolism

Question 6

Patient information (Anti-Epileptic Drugs - Levetiracetam)

Answer 6

• It might affect your ability to drive or operate machinery

- Not recommended during pregnancy and breastfeeding