Gastrointestinal (Anti-Emetic Drugs - Cyclizine)

Question 1

Exmaples of drugs (Anti-Emetic Drugs - Cyclizine)

Answer 1

• Cyclizine

Question 2

Mechanism of action (Anti-Emetic Drugs - Cyclizine)

Answer 2

• Histamine H1 receptor antagonist
• Acts on vomiting center in the medullary region
• Mild anti-cholinergic and anbti-muscarinic effects

Question 3

Indications (Anti-Emetic Drugs - Cyclizine)

Answer 3

• Nausea and vomiting
• Motion sickness
• Vertigo and dizziness
• Prophylaxis alongside chemotherapy and opiate analgesic use

Question 4

Side-effects (Anti-Emetic Drugs - Cyclizine)

Answer 4

• Headache
• Sedation
• Diarrhoea

Question 5

Important pharmacokinetics/pharmacodynamics (Anti-Emetic Drugs - Cyclizine)

Answer 5

• It can also be a central nervous system depressant

Question 6

Patient information (Anti-Emetic Drugs - Cyclizine)

Answer 6

• Avoid alcohol
• Food may reduce irritation
• Take without regard to meals