microbio - fungi Flashcards
Unicellular growth form of fungi
Yeast
Eucaryotic cells that lack chlorophyll so they cannot generate thru photosynthesis. They do require aerobic environment.
Fungi
Multicellular colonies composed of clumps of intertwined branching hyphae
Molds
Reproducing bodies of molds.
Spore
Fungi that can grow as either a yeast or mold, depending on environmental conditions and temperature (usually growing as a yeast at body temperatures).
Dimorphic fungi
Culture for fungi
Saborauds agar
Fungi that live in and utilize organic matter (soil, rotten vegetation) as an energy source.
Saprophytes
Essential sterol in fungi
Ergosterol
Antifungal drug that destroys cm (ergosterol)
Amphiteracin B and nystatin
Antifungal drug that inhibits ergosterol synthesis
Ketoconazole
Superficial fungal infection
Pityriasis versicolor
Tinea nigra
Primary manifestation of superficial fungal infections
Pigment change of the skin
Pityriasis versicolor is caused by..
Malassezia furfur
Fungi can look like spaghetti (hyphae) and meat balls (spherical yeast)
Malassezia furfur
Lipophylic yeast
Malassezia furfur
Category of cutaneous fungal infection where fungi live in the dead, horny layer of skin, hair and nails.
Dermathophytic cells
Dermatophytic cells secreted an enzyme called…
Keratinase
Fungal infection of the body
Tinea corporis
Fungal infection of the hair (scalp)
Tinea capitis
Fungal infection of the groin and scrotum
Tinea cruris
Fungal infection of the foot
Tinea pedis
Fungal infection of the nails
Tinea unguium (onchomycosis)
First line drugs for treatment of dermatophytoses
Topical imidazole
Treatment for tinea capitis and tinea unguium
Oral griseofulvin
Subcutaneous fungal infection
Sporotrichosis
Chromoblastomycosis
Microorg that causes sporotrichosis
Sporothrix schenckii
Subcutaneous-fungal infections gain entrance to the body following…
Trauma to the skin
Rose gardener’s disease
Sporotrichosis. (Sporothrix schenckii)
Cigar-shape yeast
Sporothrix schenckii
Infection from plant part trauma
Sporothrix schenckii
T or F: spores can be transmitted from person to person
False. Never, it can be acquired thru inhalation as a spore.
Systemic fungal infection.
Blastomycosis
Coccidiodomycosis
Rarest systemic fungal infection
Blastomyces
Broad-based budding yeast
Blastomyces
Causes desert rheumatism and San Joaquin fever
Coccidioides immitis
Coccidiodes immitis causes what diseases
San Joaquin fever
Desert rheumatism
Coccidiodes immitis can be stained by
India ink
Non budding spherioles
Coccidiodes immitis
Arthroconidia
Coccidiodes immitis
Most common cns fungal infection
Cryptococcus neoformans
Cryptococcus neoformans is found in nature, especially in.
Pigeon droppings
Can be found in pigeon droppings
Cryptococcus neoformans
Encapsulated yeasts
Cryptococcus neoformans
The key to diagnosis of this fungus is doing a lumbar puncture and analyzing the CSF. An India ink test is positive.
Cryptococcus neoformans
Treatment for Cryptococcus neoformans
Amphotericin B
Fluconazole (or flucytosine)
T or F: Cryptococcus neoformans is associated with AIDS.
True
Torulosis
Aseptic meningitis
Cryptococcus neoformans
Causes oral thrush
Candida albicans
Diseases caused by Candida albicans
Diaper rush
Oral thrush
Vaginitis
Cottage cheese vaginal discharge
Candida albicans
Produces pseudohyphae
Candida albicans
Fungus ball in the brain abscess
Aspergillus fumigatus
Most common in chronic sinusitis
Aspergillus fumigatus
Dichotomous branching hyphae
Aspergillus fumigatus
The fungi-like bacteria
Actinomyces
Nocardia
Lumpy jaw
Actinomyces Israeli
When examined under microscope, the pus draining from the abscess of actinomyces infection reveals yellow granules called..
Sulfur granules
Treatment for actinomyces and nocardia
SNAP
Sulfamethoxazole for Nocardia
Actinomyces is Pen G
Madura foot
Pseudallescheria boydii
Pilot’s wheel
Paracoccidiodes brasilensis
Black nasal discharge + sinusitis
Mucormycosis / rhizopus
Broad hyphae invading blood vessels walls
Mucormycosis / rhizopus
Fungal infection (previously protozoa) common in AIDS
Pneumocystis jiroveci
Stain for pneumocystis jiroveci
Silver stain
Treatment for pneumocystis jiroveci
Trimethoprim-sulfamethoxazole
Fungus that has no ergosterol
Pneumocystis jiroveci