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Med Prep > derma- mycobacterial infection > Flashcards

derma- mycobacterial infection Flashcards

0
Q

Endogenous cutaneous tb

A 
LV lupus vulgaris
SD scrofula derma
MTA metastatic tb abscess
AMT acute miliary TB 
OT orificial tb
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1
Q

exogenous cutaneous tb

A

PIT primary inoculation tb

TVC tb verrucosa cutis

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2
Q

Cutaneous TB common in infant

A

PIT

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3
Q

Cutaneous TB via opercutaneous inoculatin, occurs at inoculated site of nonimmune host

A

PIT

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4
Q

Cutaneous TB common in male

A

TVC

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5
Q

Cutaneous TB common in female

A

LV

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6
Q

Cutaneous TB via Percutaneous inoculation, occurs in inoculated site in individual with prior tb infection

A

TVC

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7
Q

Cutaneous TB common in 3rd world country and tropics

A

TVC

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8
Q

Cutaneous TB common in all ages

A

LV

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9
Q

Cutaneous TB common in adolescent and elderly

A

SD

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10
Q

Cutaneous TB common in infant and adult who are immunocompromised

A

AMTRAK

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11
Q

cutaneous TB is also Common in farmer and butchers from what species of mycobacterium

A

M. Bovis

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12
Q

Papule and painless ulcer (tuberculous chancre) in 2-4wks

A

PIT

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13
Q

Regional LA in 3-8wks

A

PIT

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14
Q

SOP of PIT

A

Exposed skin of minor injuries

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15
Q

Papule with violaceous halo (hyperkeratosis, warty, firm plaque, irregular borders)
No LA

A

TVC

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16
Q

SOP of TVC

A

Dorsolat hands and fingers

Children- Lowe ext and knees

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17
Q

Soft flat papule, ill defined with smooth surface and slightly scaly

A

LV

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18
Q

Apple jelly color on diascopy

A

LV

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19
Q

SOP of LV

A

Head and neck

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20
Q

Hyperkeratotic form of LV = soft tumorous nodule

A

Ulcerative form of LV = punched out, serpinginous

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21
Q

Firm, subQ nodule, irrev deep seated which liquifies and perforates

A

SD

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22
Q

SOP of SD

A

Parotid, submandibular, supraclavicular

Lat neck

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23
Q

Contiguous spread from affected LN

A

SD

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24
Q

Most common opportunistic infection in hiv pts in developing countries

A

TB

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25
Q

Route of cutaneous TB

A

Exogenous
Endogenous
By autoinoculation

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26
Q

Oral lesions in tb Develops when..

A

Ingestion of bovine bacilli in nonpasteurized milk

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27
Q

Tuberculous gumma

A

MTA

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28
Q

SubQ abscess, no tender, cold fluctuant to fistula and ulcer.

A

MTA

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29
Q

SOP of MTA

A

Sites of previous trauma

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30
Q

Small yellowih nodule with painful irreg ulcer with undermined borders

A

OT

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31
Q

Results form autoinoculation from progressive TB of internal organs

A

OT

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32
Q

SOP of OT

A

Oral, pharyngeal - pulmonary tb
Vulva - GU TB
Anal - intestinal TB

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33
Q

Convert form neg to Pos skin test on wks of infection

A

PIT

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34
Q

Neg skin test

A

AMT

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35
Q

May be neg or pos skin test

A

SD
MTA
OT

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36
Q

Pos skin test

A

LV

TVC

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37
Q

Pit, without treatment, usually resovles within __mos with some residual scarring

A

12 mos

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38
Q

LV develops at site of

A

PIT

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39
Q

Cutaneous TB which are limited to skin and can be excised

A

PIT

TVC

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40
Q

Management of cutaneous TB

A

Prolonged Treatment with at least 2 drugs

Isoniazid and rifampin (9mos)

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41
Q

Age of fish tank granuloma

A

20-40yrs old

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42
Q

Fish tank granuloma is caused by

A

M. Marinum

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43
Q

Fish tank granuloma is common in m/f

A

Male

44
Q

Incubation period of Fish tank granuloma

A

1wk -2mos

45
Q

Fish tank granuloma is benign and self limited. May remain active but a singe papulonodular lesion resolves in

A

3mos to 3yrs

46
Q

Prophylaxis for Fish tank granuloma

A

Wear waterproof gloves

47
Q

Drug of choice for Fish tank granuloma

A

Clarithromycin

Also ethambutol and rifampin

48
Q

Age of buruli /bairnsdale ulcer

A

Children and young adult

49
Q

Etiology of buruli /bairnsdale ulcer

A

M. Ulcerans

50
Q

Sex of buruli/bairnsdale ulcer

A

Male

51
Q

Got from pricks or cuts from plants (wet, marshy, swampy sites)

A

Buruli / bairnsdale ulcer

52
Q

Buruli secretes what toxin

A

Polyketide toxin (mycolactone)

53
Q

Incubation period in buruli/bairnsdale

A

3mos

54
Q

Painful/painless ulcer in buruli/bairnsdale

A

Painless subQ ulceration

55
Q

Why should apply heat to buruli ulcer

A

Because ulcerana prefer cold temp

56
Q

T or F: antimycobacteril is effective to buruli ulcer

A

False. Ineffective

57
Q

Hansen’s disease

A

Leprosy

58
Q

Chronic granulomatous disease

A

Leprosy

59
Q

Mycobacterium leprae prefers hot/cold temp

A

Prefers cold temp

60
Q

T or F: Mycobacterium are obligate afb

A

True

61
Q

Localized skin involvement and peripheral n involvement

Few org in skin biopsies

A

Tuberculoid TLC

62
Q

Generalized involvement
Skin, upper respi mm, RES, adrenal, tested
Many bacilli

A

Lepromatous LL

63
Q

Combi of tuberculoid and lepromatous

Many bacilli

A

Borderline dimorphic BL

64
Q

Classif of leprosy:
Very early lesion
Host response is indeterminate rather than diagnosis

A

Indeterminate and transitional form

65
Q

Leprosy common in M/F

A

Male

66
Q

T or F: leprosy has direct relations between skin color and severity of disease

A

False, inverse relation

67
Q

Main reservoir in leprosy

A

Humans

68
Q

Other than human, what is the reservoirs of leprosy

A

Armadillo
Mangabey monkey
Chimpanzees

69
Q

Mode of trnasmiission of leprosy

A

Uncertain
Droplet infection
Contact with infected soil
Insect vector

70
Q

Clinical expression of body to leprosy infection

A

Development of granuloma

71
Q

Downgrading and reversal reaction

A

Lepra type 1 reaction

72
Q

Disease in lepra type 1

A

Borderline disease BT BL

73
Q

Why does downgrading occurs

A

Before therapy

74
Q

When does reversal occurs

A

In response to therapy

75
Q

Lepra type: acutely inflamed, with edema (face, hands, feet) and pain

A

Type 1

76
Q

Erythema nodosum leprosum

A

Lepra 2

77
Q

Patients in lepra type 2

A

LL

78
Q

When does lepra type 2 occurs

A

After initiation of therapy (within first 2yrs)

79
Q

Lepra type: painful red skin nodules superficially and deeply. Form abscess and ulcer on face and ext

A

Lepra type2

80
Q

Lepra type: irreg erythema plaque. Many resolve spont or necrosis with ulceration

A

Lucio’s reaction

81
Q

Lepra type: shallow large polygonal sloughing ulceration

A

Lucio’s reaction

82
Q

Lepra type: variant of ENL or sec to arteriolar occlusion

A

Lucio’s reaction

83
Q

Leprosy type: Hypo pigmented hypesthetic macule with raised edges (becomes atopic or depressed)

A

TT, BT

84
Q

Leprosy type: its advanced lesion results to anesthetic and devoid of skin appendages

A

TT, BT

85
Q

TT/BT: may resolve spont, not associated with Lepra reaction

A

TT

86
Q

TT/BT: do not heal spont, type 1 lepra reaction

A

BT

87
Q

Nerve involved in TT or BT

A

Ulnar nerve (pinprick test, temp, vibration)

88
Q

Incubation period of tuberculoid leprosy

A

2-40yrs (5-7yrs)

89
Q

Leprosy type: insidious onset and painless. PNS with persistent or recurrent painful numbness. no trauma

A

TT! BT

90
Q

Leprosy type: punched out patches

A

Borderline leprosy

91
Q

Leprosy type: diffuse derma infiltration and thickened Dermis

A

Diffuse lepromatosis

92
Q

T or F: nerve involvement in LL is more extensive than TT

A

True

93
Q

Leprosy type: histoid nodule

A

LL

94
Q

PE of leprosy extremities

A

Sensory neuropathy
Plantar ulcers
Ulnar and peroneal palsy
Charcot jts

95
Q

PE of leprosy nose

A

Chronic nasal congestion
Epistaxis
Saddle nose deformity

96
Q

PE of leprosy eyes

A

Cranial nerve palsies
Lagophthalmus
LL: anterior chamber
Corneal damage

97
Q

PE of leprosy testes

A

Hypogonadism

98
Q

Pauli-bacillary

A

1-5 lesions
- afb
TT and BT

99
Q

Multibacillary

A

> 5 lesions
+ afb
BB, LL, BL

100
Q

Treatment for paucibacillary

A

Dapsone plus rifampin for 6mos

101
Q

Treatment for multi bacillary

A

Dapsone
Clofazimine
Rifampin
Monthly for 1yrn

102
Q

Slit skin smear

A

Leprosy

103
Q

M. Leprae has not been cultured in vitro. It grows when inoculated into the

A

Mouse foot pad

104
Q

Cardinal findings in leprosy

A

Pt from endemic area
Skin lesion with diminished or loss of sensation
Enlarged peripheral nerves
M. Leprae in skin

105
Q

T or F: amyloidisis can complicate long standing leprosy

A

True

106
Q

Course and prognosis of BT

A

2-4mos

107
Q

Course and prognosis of BL

A

9mos

108
Q

Course and prognosis of lepra type 2

A

Within 2 yrs

Med Prep (52 decks)

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