gyne- cervical and ovarian ca Flashcards

0
Q

Cervical SCCA/AdenoCa: associated with early and freq sexual contact

A

SCCA

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1
Q

Cervical SCCA/AdenoCa: most common cervical ca

A

SCCA

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2
Q

Cervical SCCA/AdenoCa: not affected by sexual contact

A

Adenoca

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3
Q

Cervical SCCA/AdenoCa: associated with sexual contact and cervical viral infection

A

SCCA

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4
Q

Subtypes of cervical SCCA

A

Large cell( keratinizing and non keratinizing)
Small cell
Verrucous

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5
Q

Cervical ca associated with diethylstilbestrol exposure

A

Clear cell cervical ca

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6
Q

Subtypes of cervical adenoca

A
Typical (endocervical)
Endometrioid
Clear cell
Adenoid cystic
Adenoma malignum
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7
Q

Basaloid cylindroma

A

Adenoid cystic of cervical ca

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8
Q

Minimal deviation adenoca

A

Adenoma malignum of cervical ca

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9
Q

Mixed cervical ca

A

Adenosquamous

Glassy cell

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10
Q

Keratinizing/nonkeratinizing:

IRREG NESTS of squamous cells forming several PEARLS separated by fibrous stroma

A

Keratinizing

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11
Q

Keratinizing/nonkeratinizing:

Discrete islands of UNIFORM large cells with abundant CYTOPLASM separated by fibrous stroma

A

Nonkeratinizing LCCA

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12
Q

How many years younger is Small cell cervical ca to SCCA?

A

10y.o

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13
Q

Small cell cervical ca is an aggressive ca which may metastasize to…

A

Bone
Liver
Skin
Brain

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14
Q

Verrucous ca is a warty, large, bulbous mass wc is similar to

A

Vulva

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15
Q

Risk factors for cervical adenocarcinoma

A

HPV DNA
OCP use
Lack of cervical cytologic screening

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16
Q

Clear cell adenoca of cervix is histologically similar to…

A

Vagina

Ovary

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17
Q

T or F: clear cell adenoca can develop simultaneously

A

True

18
Q

Adenoid cystic cervical ca resembles…

A

Cylindroma of salivary gland or breast origin

BCCa of Skin

19
Q

T or f: mixed cervical ca is a hospital diagnosis

A

True

20
Q

T or f: adenosquamous ca occur freq in nonpregnant women

A

False. Occurs in pregnant women

21
Q

Glass cell cervical ca is a SMALL/LARGE cell containing cyto with ground glass appearne which tends to metastasize to ____

A

Large cells

Metastasize in lymph nodes

22
Q

Mixed cervical ca

A

Adenosquamous ca

Glass cell ca

23
Q

Clinical features of cervical ca

A

Bleeding or brownish discharge
Ff douching or intercourse
Spont in between men’s

24
Q

Late manifestations of cervical ca which usually means extensive spread of ca

A

Back pain
Loss of appetite
Weight loss

25
Q

Age of cervical ca

A

40-60

26
Q

Preinvasive intraepithelial cervical ca age

A

20

27
Q

Diagnostic tests for cervical ca

A

Pap smear
Colposcopy
Endocervical curettage
Biopsy

28
Q

Excisional/punch biopsy is preferable in cervical ca

A

Excisional biopsy

29
Q

Helps in selecting the biopsy sight where growth is a obvious in cervical ca

A

Schiller’s test/acetic acid

30
Q

Biopsy for early cases of cervical ca

A

Cone biopsy

31
Q

Used in VIA

A

3-5% Acetic acid

32
Q

Used in schiller’s test

A

Iodine

33
Q

Characteristic of good screening tool

A
High sn and sp
Applied to asymptomatic women
Diagnosis of disease at premalignant 
Easily applied to large grp
Reasonable cost
34
Q

Adeq specimen of Pap smear

A

Squamo columnar junction

35
Q

Sn and sp of Pap smear

A

Sn 50%

Sp 95%

36
Q

Best yield Pap smear

A

Arye spatula plus endocervical brush

37
Q

Developed as a uniform system of terminology which provides clear guidance for clinical management

A

Bethesda system

38
Q

Most imp quality assurance of bethesda system

A

Evaluation of specimen adequacy

39
Q

When the degree of atypia is not sufficient to warrant diagnosis of SIL

A

ASC

40
Q

Management for ASC

A

Observe, ff up

41
Q

ASC-H have a significantly higher predictive value for ___ than ASC-US

A

CIN 2 or 3

42
Q

Management for ASC-US and ASC-H

A

Biopsy