gyne- cervical and ovarian ca Flashcards

0
Q

Cervical SCCA/AdenoCa: associated with early and freq sexual contact

A

SCCA

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1
Q

Cervical SCCA/AdenoCa: most common cervical ca

A

SCCA

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2
Q

Cervical SCCA/AdenoCa: not affected by sexual contact

A

Adenoca

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3
Q

Cervical SCCA/AdenoCa: associated with sexual contact and cervical viral infection

A

SCCA

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4
Q

Subtypes of cervical SCCA

A

Large cell( keratinizing and non keratinizing)
Small cell
Verrucous

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5
Q

Cervical ca associated with diethylstilbestrol exposure

A

Clear cell cervical ca

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6
Q

Subtypes of cervical adenoca

A
Typical (endocervical)
Endometrioid
Clear cell
Adenoid cystic
Adenoma malignum
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7
Q

Basaloid cylindroma

A

Adenoid cystic of cervical ca

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8
Q

Minimal deviation adenoca

A

Adenoma malignum of cervical ca

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9
Q

Mixed cervical ca

A

Adenosquamous

Glassy cell

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10
Q

Keratinizing/nonkeratinizing:

IRREG NESTS of squamous cells forming several PEARLS separated by fibrous stroma

A

Keratinizing

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11
Q

Keratinizing/nonkeratinizing:

Discrete islands of UNIFORM large cells with abundant CYTOPLASM separated by fibrous stroma

A

Nonkeratinizing LCCA

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12
Q

How many years younger is Small cell cervical ca to SCCA?

A

10y.o

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13
Q

Small cell cervical ca is an aggressive ca which may metastasize to…

A

Bone
Liver
Skin
Brain

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14
Q

Verrucous ca is a warty, large, bulbous mass wc is similar to

A

Vulva

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15
Q

Risk factors for cervical adenocarcinoma

A

HPV DNA
OCP use
Lack of cervical cytologic screening

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16
Q

Clear cell adenoca of cervix is histologically similar to…

A

Vagina

Ovary

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17
Q

T or F: clear cell adenoca can develop simultaneously

18
Q

Adenoid cystic cervical ca resembles…

A

Cylindroma of salivary gland or breast origin

BCCa of Skin

19
Q

T or f: mixed cervical ca is a hospital diagnosis

20
Q

T or f: adenosquamous ca occur freq in nonpregnant women

A

False. Occurs in pregnant women

21
Q

Glass cell cervical ca is a SMALL/LARGE cell containing cyto with ground glass appearne which tends to metastasize to ____

A

Large cells

Metastasize in lymph nodes

22
Q

Mixed cervical ca

A

Adenosquamous ca

Glass cell ca

23
Q

Clinical features of cervical ca

A

Bleeding or brownish discharge
Ff douching or intercourse
Spont in between men’s

24
Late manifestations of cervical ca which usually means extensive spread of ca
Back pain Loss of appetite Weight loss
25
Age of cervical ca
40-60
26
Preinvasive intraepithelial cervical ca age
20
27
Diagnostic tests for cervical ca
Pap smear Colposcopy Endocervical curettage Biopsy
28
Excisional/punch biopsy is preferable in cervical ca
Excisional biopsy
29
Helps in selecting the biopsy sight where growth is a obvious in cervical ca
Schiller's test/acetic acid
30
Biopsy for early cases of cervical ca
Cone biopsy
31
Used in VIA
3-5% Acetic acid
32
Used in schiller's test
Iodine
33
Characteristic of good screening tool
``` High sn and sp Applied to asymptomatic women Diagnosis of disease at premalignant Easily applied to large grp Reasonable cost ```
34
Adeq specimen of Pap smear
Squamo columnar junction
35
Sn and sp of Pap smear
Sn 50% | Sp 95%
36
Best yield Pap smear
Arye spatula plus endocervical brush
37
Developed as a uniform system of terminology which provides clear guidance for clinical management
Bethesda system
38
Most imp quality assurance of bethesda system
Evaluation of specimen adequacy
39
When the degree of atypia is not sufficient to warrant diagnosis of SIL
ASC
40
Management for ASC
Observe, ff up
41
ASC-H have a significantly higher predictive value for ___ than ASC-US
CIN 2 or 3
42
Management for ASC-US and ASC-H
Biopsy