Mechanisms of infectious disease Flashcards

1
Q

What is a host?

A

organism capable or allowed to be infected

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2
Q

What is infectious disease

A

state if disease having another interaction with a organism

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3
Q

What is Colonization?

A

organisms living and multiplying and living in the host

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4
Q

What is microflora?

A

Bacteria that naturally live on surfaces on body

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5
Q

What is virulence?

A

Indicates degree to which organism will produce disease

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6
Q

What is the difference between microflora and pathogen?

A

-Microflora normally live on our body either in Gi tract or our skin. They are mostly useful bacteria
-pathogens cause disease and they can take over when body is weak or pathogens come in from the outside

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7
Q

What is the triad of infectious disease model

A

-The environment and host interact
-The host and agent interact
-Agent and environment interact and they all interact with each other

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8
Q

What are agents of infectious disease?

A

-Prions
-Viruses
-bacteria
-Rickettsiaceae
-chlamydiacease
-fungi
-parasites

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9
Q

What are virsuses?

A

-Smallest structure that can cause illnesses
-No cellular structure and protein structure
-Can not replicate outside cell, need cells RNA and DNA to make more virus

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10
Q

***Microorganisms
Describe fungi

A

eukaryotctes
-Yeast and mold, they require a cooler temperature than body core temp to replicate.
-Most infections happen outside of the body and
-mostly on skin and
-can cause life threatening when the host does not have enough strenght to fight back the mold and yeast

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11
Q

***Microorganisms
Describe bacteria

A

prokaryotes( no nucleus)
-use host for food and shelter
-produces biofilms that allow it to stick and colonize the tissue it invades

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12
Q

**Other microorganism
Where is protozoa found?

A

Common in water

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13
Q

**Other microorganism
What are prions

A

Proteins found in infected animals and can be ingested from infected meat

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14
Q

**Other microorganism
Where can worms be found

A

Found within body space

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15
Q

Describe rickettsiaceae, anaplasmatacecae, chlamydiaceae,coxiella

A

Other organisms that have viral and bacterial characteristics that can cause variety of illness
-chlamydia is more common than the others
-They produce asexually
-They are similar to bacteria

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16
Q

What are types of parasites?

A

Protozoa
Helminths
Arthropods

17
Q

describe parasites

A

small animals that infect by invading larger animals and setting up a home, so the animals can transmit the illness to humans

18
Q

What is epidemology

A

science of studying how disease occurs and progresses

19
Q

What us incidence

A

Number of new cases that happen

20
Q

What is prevalence

A

total amount of active cases at any given time

21
Q

What do you need for classifcation of infectious disease?

A

Incidence
portal of entry- how it enetered the body
source of transmission- how it penetrates
symptoms
how long the disease last
What part of the body gets infected
Virulence factors-how sick does that person get

22
Q

What is endemic disease?

A

A disease found in specific geographic region that is expected and stable
If there is a pattern disease occurring in a geographic area

23
Q

What is epidemic

A

Unexpected increase of a disease
like influenza unexpected cases that comes every year

24
Q

What is pandemic

A

Spread of disease globally

25
Q

***Location
What is nosomial?

A

Occurred within hospital patients

26
Q

***Location of disease
What is community required

A

Disease acquired outside healthcare facilities in the community and brought into the hospital setting

27
Q

***Symptomatology
What is specific symptoms ?

A

Talk about site of infections like diahrrhea,rash, hemmorage, pneumonia

28
Q

***Symptomatology
What are non specific symptoms?

A

Shared by number of infectious disease like fever muscle pain, headache which can occur with anything

29
Q

***Symptomatology
What are obvious symptoms?

A

predictable pattens like chicken pox or measles

30
Q

***Symptomatology
What are covert symptoms ?

A

Symptoms under the surface that require laboratory testing to confirm

31
Q

***Disease course of infection
Whatt is incubation period?

A

pathogen has infected host and actively replicating in background
-no symptoms like prep period of pathogen infecting host

32
Q

***Disease course of infection
What is the prodomal stage ?

A

Intial appearance of symptoms
-symptoms are vague and not specific

33
Q

***Disease course of infection
What is the acute stage?

A

-Lots of replication, proliferation of patho gen
and symptoms are more prounounced

34
Q

***Disease course of infection
What is the convalescent stage ?

A

-Pathogen is eliminated by body or medication

35
Q

***Disease course of infection
What is the resolution stage?

A

The pathogen has completely eliminated from the body

36
Q

bioteerrorism
What is category A agents

A

plague
tularemia
smallpox
hemorrhagic fever viruses

37
Q

bioterrorism
What is category B agents

A

Agents of food borne and water born disease
Agents of zoonotic infections
vira; encephalitides
toxins from castor bean

38
Q

Bioterrorism
what are categories C agents

A

Mycobacterium tuberculosis
Nipah virus hantavirus
Tick borne and yellow fever virsuses
cryptosporidum parvum