Chapter 9 inflammation, Tissue repair, and wound healing Flashcards
What is tissue repair?
-The way the body responds to injury to get back to normal
What is tissue regeneration?
-Cells of the same type replace injured tissue
What is Fibrous tissue repair?
-Repair by replacing with connective tissues and scar formation,
-Is for a more complicated wound
What is granulation tissue?
-Connective tissue that has all ingredients to build tissue from the bottom up
-Scar formation builds on the granulation tissue
Whats the difference between primary and secondary intention?
Primary intention
-Tiny and can be closed by sutures, staples, etc after surgery or injury
-Straight edge, well approximated
-More intentional
-Common with surgery, paper cuts
Secondary intention
-Wound is deeper and thicker
-Can’t be healed by sutures and space will be filled creating scar
-Less intentional
-Scar will probably start to go
-Longer healing time
-Like a pressure injury
What are the stages of wound healing?
Hemostasis is the first step. Happens to stop bleeding , through vasoconstriction and activating platlets so bleeding can stop
1) Inflammatory stage
-Begins at the time of injury
-Blood clot forms
-Migration of phagocytic WBC into the wound site
2) Proliferative phase
-New tissue fills the wound
-Fibroblast: Connective tissue that cell synthesizes and secretes collagen, proteglycans and glycoproteins needed for wound healing
3) Wound contraction and remodeling phase
-About 3 weeks after injury, fibrous scar developes ; remodeling of scar tissue
What can cause impaired wound healing?
-Malnutrition
-Impaired blood flow and oxygen delivery
-Impaired inflammatory and immune response
-Infection
-Wound separation
-Foreign bodies
-Age effects
**Types of exudate
What is a serious exudate?
Water fluid low in protein
**Types of exudate
What is hemorrhage exudate?
Leakage of RBC from the capillaries
**Types of exudate
What fibrinous exudate ?
Large amounts of fibrinogen, forms a thick and sticky meshwork
**Types of exudate
What is a membranous exudate?
Developed in mucous membranes surfaces and are compose of necrotic cells, emneshed in fibro-purulent exudate
**Types of exudate
What is purulent exudate?
Contains pus, composed of degraded WBC, proetins, and tissue debris
**Types of exudate
What is abscess exudate ?
Localized area of inflammation containing purulent exudate
**Types of exudate
What is ulceration?
Epithelial surfaces becomes necrotic