Immunomodulators Flashcards
1
Q
What are HAMA?
A
Human Anti-Murine Antibodies
2
Q
ADCC is _________.
A
antibody-dependent cell cytolysis (the method of NK killing)
3
Q
What is ZMapp?
A
A combination of three monoclonal antibodies to ebola made in tobacco plants
4
Q
-omab antibodies are _________; -ximab are ______; -zumab are _______; and -umab are ________.
A
murine; chimeric; humanized; human
5
Q
Natural killer cells have no _______, but they kill cells similar to CTLs; they normally kill ________.
A
VDJ rearrangement; damaged or overly stressed cells
6
Q
What are three downsides to using immunosuppressive medications?
A
(1) increased risk of cancer; (2) increased risk of infections; and (3) toxicity
