Histology of the Thymus and Peripheral Lymphoid Organs

Question 1

The ______ lymphatic is found in the hilum of the lymph node.

Answer 1

efferent

Question 2

The cortex is ________.

Answer 2

mostly B cells

Question 3

The paracortex is mostly _______.

Answer 3

T cells

Question 4

_______ are where B cells have been stimulated; they are found within _____.

Answer 4

Germinal centers; follicles

Question 5

The arterioles and venules are both found in the _______.

Answer 5

hilum of the lymph node

Question 6

What are high endothelial venules?

Answer 6

Highly permeable venules found in the paracortex or cortex that allow diapedesis of lymphocytes

Question 7

_______ divide the follicular centers.

Answer 7

Trabeculae

Question 8

Bacteria, macrophages, and large particles get stuck in _________.

Answer 8

reticular fibers

Question 9

_________ is a disease in which bacteria evade the immune system and divide in the lymph nodes.

Answer 9

Bubonic plague

Question 10

List the cell types found in germinal centers.

Answer 10

B cells, Tfh, and APCs

Question 11

As with lymph nodes, the thymus is also divided by _________ into pseudolobules.

Answer 11

trabeculae

Question 12

______ serve as the skeleton of the thymus.

Answer 12

Stromal cells

Question 13

______ and ______ are found within the trabeculae of the thymus.

Answer 13

Arterioles; venules

Question 14

There are only _______ lymphatics in the thymus.

Answer 14

efferent

Question 15

The _______ cells form the blood-thymus barrier that prevent antigens from entering the thymus.

Answer 15

reticulo-endothelial cells (which surround the connective tissue around blood vessels)

Question 16

Hassell’s (corpuscles) are ____.

Answer 16

look up… missed during lecture

Question 17

In the thymus, blood vessels bypass the _____ via trabeculae and directly enter the _____.

Answer 17

cortex; medulla

Question 18

There is no ______ lymph supply to the thymus.

Answer 18

afferent

Question 19

The two arteries that supply the thymus are the ______.

Answer 19

internal thoracic and inferior thyroid

Question 20

Describe the path of lymph through lymph nodes.

Answer 20

Afferent lymphatic, subcapuslary sinus, trabecula, trabecular sinus, cortex, medulla, efferent lymphatic

Question 21

Circulating T and B lymphocytes recognize the ________ of lymph nodes, allowing them to enter and interact with lymph cells.

Answer 21

high endothelial venules

Question 22

When the splenic artery splits into smaller tributaries, the tributaries are ______.

Answer 22

sheathed in T lymphocytes (white pulp)

Question 23

In the thymus, the more mature T cells are in the _____.

Answer 23

medulla, and the immature cells are on the periphery (cortex)

Question 24

Hassall’s corpuscles are ______.

Answer 24

collections of reticular cells thought to be important in suppressing autoimmune dysfunction

Question 25

In the spleen, macrophages are predominantly found in the ________.

Answer 25

red pulp (to destroy senescent RBCs)