Histology of the Thymus and Peripheral Lymphoid Organs Flashcards
The ______ lymphatic is found in the hilum of the lymph node.
efferent
The cortex is ________.
mostly B cells
The paracortex is mostly _______.
T cells
_______ are where B cells have been stimulated; they are found within _____.
Germinal centers; follicles
The arterioles and venules are both found in the _______.
hilum of the lymph node
What are high endothelial venules?
Highly permeable venules found in the paracortex or cortex that allow diapedesis of lymphocytes
_______ divide the follicular centers.
Trabeculae
Bacteria, macrophages, and large particles get stuck in _________.
reticular fibers
_________ is a disease in which bacteria evade the immune system and divide in the lymph nodes.
Bubonic plague
List the cell types found in germinal centers.
B cells, Tfh, and APCs
As with lymph nodes, the thymus is also divided by _________ into pseudolobules.
trabeculae
______ serve as the skeleton of the thymus.
Stromal cells
______ and ______ are found within the trabeculae of the thymus.
Arterioles; venules
There are only _______ lymphatics in the thymus.
efferent
The _______ cells form the blood-thymus barrier that prevent antigens from entering the thymus.
reticulo-endothelial cells (which surround the connective tissue around blood vessels)
Hassell’s (corpuscles) are ____.
look up… missed during lecture
In the thymus, blood vessels bypass the _____ via trabeculae and directly enter the _____.
cortex; medulla
There is no ______ lymph supply to the thymus.
afferent
The two arteries that supply the thymus are the ______.
internal thoracic and inferior thyroid
Describe the path of lymph through lymph nodes.
Afferent lymphatic, subcapuslary sinus, trabecula, trabecular sinus, cortex, medulla, efferent lymphatic
Circulating T and B lymphocytes recognize the ________ of lymph nodes, allowing them to enter and interact with lymph cells.
high endothelial venules
When the splenic artery splits into smaller tributaries, the tributaries are ______.
sheathed in T lymphocytes (white pulp)
In the thymus, the more mature T cells are in the _____.
medulla, and the immature cells are on the periphery (cortex)
Hassall’s corpuscles are ______.
collections of reticular cells thought to be important in suppressing autoimmune dysfunction
In the spleen, macrophages are predominantly found in the ________.
red pulp (to destroy senescent RBCs)
