Final Exam Review Flashcards
Dactylitis is a sign of ___________.
reactive arthritis
Lesch-Nyhan is deficiency of _________.
HGPRT
The systemic effects of RA are mediated by ________.
IL-6
Describe ANA.
ANA are high in asymptomatic people, so the lab value is not very useful for diagnosing stuff.
Gout ______ have systemic symptoms.
can
Those with HIV immunosuppression can still respond to __________.
extracellular pathogens
Those with type I vWD have ______ factor VIII function.
55%
In HIV, why do CD4+ cells lyse?
They lyse when virions bud.
HIV elite controllers are ________ and make _________.
HLA-B57; more diversity of CTLs
PPi levels are elevated in __________.
both CPDD and osteoarthritis
Reactive arthritis presents with ________.
Reiter’s triad: conjunctivitis, urethritis, and arthritis
Thrombin activates platelets by ___________.
cleaving protease activated receptor 1 (PAR1)
Takayasu’s arteritis is shown by ___________.
fever, night sweats, skin nodules, weak pulses, ocular disturbances,
RA begins with _________ and proceeds to _________.
inflammation of the synovium; arrival of type A and B cells and increase in synovial lining
Platelet GP VI binds to __________.
collagen
Only ______ percent of HLA-B27 people develop ankylosing spondylitis.
2
Tumors that show embryonic antigens are _______.
oncofetal
Western blots are more ______ than ELISA.
specific
Chimeric antibodies can create a cytokine storm by ___________.
activating the CD3 receptor on T cells
The severity of RA correlates with __________.
QKRAA in the HLA-DR4/HLA-DR1
The earliest even in type III immune complexes is _________.
release of platelet-activating factors
In chronic ITP, the only time platelets are transfused is _________.
in hemorrhagic emergencies
People should stop taking aspirin _________ before a procedure.
10 days
