Immunodiagnosis

Question 1

Double positive T cells (that is, those with _________) are only found in the _________.

Answer 1

CD4 and CD8; thymus

Question 2

Does unsecreted IgA (i.e., IgA found in the blood) have secretory component?

Answer 2

No, that is made by epithelial cells

Question 3

Children are born with _______ thymuses.

Answer 3

enormous

Question 4

ELISAs start with __________.

Answer 4

something stuck to the bottom of the test tube; for instance, if you want to test for the presence of antibody to HIV, then you use a tube coated with HIV antigen and run patient plasma over it

Question 5

The pro-B cell stage is the first stage, and it is marked by ______; it is finished when ________.

Answer 5

no surface receptors; VDJ shuffling is complete

Question 6

Pre-B cells have _________.

Answer 6

only light chains on their surfaces

Question 7

Immature B cells have __________.

Answer 7

surface IgM

Question 8

Mature B cells have ___________.

Answer 8

surface IgM and surface IgD