IASM 71: Antibiotics in BRIEF + Vaccines Flashcards

1
Q

Name 2 types of antibiotics having the target site at

Cell wall

A

Beta Lactam

Glycopeptides

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2
Q

Name 1 types of antibiotics having the target site at

DNA Synthesis

A

Fluoroquinolones

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3
Q

Name 1 types of antibiotics having the target site at

RNA Synthesis

A

Rifamycin

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4
Q

Name 2 types of antibiotics having the target site at

30s Unit of Ribosomes

A

Tetracycline

Aminoglycosides

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5
Q

Name 1 types of antibiotics having the target site at

50s Unit of Ribosomes

A

Macrolides

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6
Q

Beta Lactam

Name the Target site

A

Cell wall

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7
Q

Glycopeptides

Name the Target site

A

Cell wall

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8
Q

Fluoroquinolones

Name the Target site

A

DNA Synthesis

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9
Q

Rifamycin

Name the Target site

A

RNA Synthesis

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10
Q

Tetracycline

Name the Target site

A

30s Unit of Ribosome

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11
Q

Macrolides

Name the Target site

A

50s Unit of Ribosome

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12
Q

Aminoglycosides

Name the Target site

A

30s Unit of Ribosome

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13
Q

Concept of Bactericidal and Bacteriostatic

  • Bactericidal: Kills ________% of the target microbe
  • Bacteriostatic: ________ the growth of the microbe, but will not be killing it
A

Concept of Bactericidal and Bacteriostatic

  • Bactericidal: Kills 99.9% of the target microbe
  • Bacteriostatic: Inhibit the growth of the microbe, but will not be killing it
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14
Q

Consider the following types of Antibiotics:
Which types are Bactericidal?
Which types are Bacteriostatic?

  • Aminoglycoside
  • Beta-lactam
  • Fluoroquinolone
  • Macrolide
  • Tetracycline
  • Vancomycin (a type of Glycopeptide)
A

Consider the following types of Antibiotics:
Which types are Bactericidal?
Which types are Bacteriostatic?

  • Aminoglycoside- Bactericidal
  • Beta-lactam- Bactericidal
  • Fluoroquinolone- Bactericidal
  • Macrolide- Bacteriostatic
  • Tetracycline- Bacteriostatic
  • Vancomycin- Bactericidal
(BAFV = Bactericial)
(TM = Bacteriostatic. 他媽,殺不死!)
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15
Q

Name 2 Examples for

Beta Lactam

A

Penicillin

Cephalosporin

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16
Q

Name 2 Examples for

Fluoroquinolones

A

Ciprofloxacin
Levofloxacin

Fluoroquinolones = ‘floxacin’

17
Q

Name 2 Examples for

Macrolides

A

Erythromycin
Azithromycin

Macrolide; ‘mycin’

18
Q

Name 1 Examples for

Tetracycline

A

Doxycycline

19
Q

Name 2 Examples for

Aminoglycosides

A

Amikacin
Gentamicin
Tobramycin

要死記啦

20
Q

Name 1 Examples for

Glycopeptides

A

Vancomycin

21
Q

Name 1 Examples for

Rifamycin

A

Rifampin

22
Q
Penicillin
Name the class of antibiotic
A

Beta-lactam

23
Q
Cephalosporin
Name the class of antibiotic
A

Beta-lactam

24
Q
Ciprofloxacin
Name the class of antibiotic
A

Fluoroquinolone

25
Q
Levofloxacin
Name the class of antibiotic
A

Fluoroquinolone

26
Q
Erythromycin
Name the class of antibiotic
A

Macrolide

27
Q
Azithromycin
Name the class of antibiotic
A

Macrolide

28
Q
Doxycycline
Name the class of antibiotic
A

Tetracycline

29
Q
Amikacin
Name the class of antibiotic
A

Aminoglycosides

30
Q
Gentamicin
Name the class of antibiotic
A

Aminoglycosides

31
Q
Tobramycin
Name the class of antibiotic
A

Aminoglycosides

32
Q
Vancomycin
Name the class of antibiotic
A

Glycopeptide

33
Q
Rifampin
Name the class of antibiotic
A

Rifamycin

34
Q

Consider Live Attenuated Vaccine

  • Name 1 advantage
  • Name 1 disadvantage
A

Consider Live Attenuated Vaccine

  • Name 1 advantage: Mimic Natural infection
  • Name 1 disadvantage: The vaccine strain might cause disease
35
Q

Consider Inactivated Vaccine

  • Name 1 advantage
  • Name 1 disadvantage

Name 2 ways to improve the immunogenicity of inactivated vaccines?
1.
2.

A

Consider Inactivated Vaccine

  • Name 1 advantage: less immunogenic
  • Name 1 disadvantage: Shorter duration of protection

Name 2 ways to improve the immunogenicity of inactivated vaccines?

  1. Add Adjuvant
  2. Protein Conjugation
36
Q

Name 1 advantage for Passive Immunization

A

Name 1 advantage for Passive Immunization

- Immediate protection provided