IASM 25: Blood Cells Flashcards

1
Q

What is the meaning of haematopoiesis

A

Formation of blood cells

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2
Q

Where is the formation of blood cells

A

Red bone marrow

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3
Q

Bone Marrow is a type of _____ tissues

A

Connective tissues

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4
Q

Throughout ageing, there is ____ in red bone marrow, and ____ in yellow bone marrow

A

Decrease in red

increase in yellow

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5
Q

Name 2 locations of red bone marrow in adults

A

Proximal end of bones

Axial skeleton

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6
Q

What is the stimulus of Erythropoiesis

A

Hypoxia

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7
Q

Where is Erythropoietin majorly released

A

Kidney

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8
Q

In which stage is the nucleus reduced in size and ejected during erythropoiesis

A

Proerythroblast

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9
Q

Where is erythrocytes broken down

Name 2 locations

A

Liver

Spleen

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10
Q

What is the fate of Heme and Globin after the break down of haemoglobin

A

Heme: Becomes bile egested in the faeces; iron is reused
Globin: Hydrolysis to form amino acids

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11
Q

Name 3 types of granulocytes under WBCs

A

Neutrophils
Basophils
Eosinophils

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12
Q

Name 3 types of agranulocytes under WBCs

A

Monocytes/ Macrophages
Lymphocytes
Natural Killer Cells

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13
Q

What is the most abundant type of WBCs

A

Neutrophils

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14
Q

Neutrophils are polymorphonuclear

What does that mean

A

Having lobulated nucleus connected by chromatin

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15
Q

An older neutrophil has more/less lobes

A

More

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16
Q

The granules of basophils are basophilic, they are stained to what colour?

A

Purple blue

17
Q

Name 2 features of Eosinophils

A
Bilobed nucleus
Eosinophilic granules (stained red)
18
Q

Monocytes have a nucleus with what shape?

A

Kidney or horse shoe shape

19
Q

What shape of nucleus does lymphocytes have?

A

Round shape

20
Q

Which type of lymphocyte is more common

Small or large

A

Small (90%)

21
Q

A large lymphocyte means that it has ____ cytoplasm

more or less

A

More

22
Q

What are thrombocytes

A

Platelets

23
Q

Does platelets have nucleus

A

no

24
Q

Production of platelets are regulated by _______

A

thrombopoietin

25
Q

Where is thrombopoietin produced (major)

A

liver