IASM 26: Skin

Question 1

What is the largest organ in human body

Answer 1

Skin

Question 2

What are the 3 layers of skin

Answer 2

Epidermis
Dermis
Subcutis

Question 3

Main cell type of Epidermis?

Answer 3

Keratinocytes

Question 4

Name 1 feature of the epidermis layer

Answer 4

Stratified

Question 5

There are 4 layers in the Epidermis layer, arrange it from the top to the bottom

Basale, Corneum, Granulosum, Spinosum

Answer 5

Corneum
Granulosum
Spinosum
Basale

Question 6

What are the 2 major components of Dermal-epidermal junction

Answer 6

Protein

Glycoprotein

Question 7

The basement membrane between epidermis and dermis is also called

Answer 7

Dermal epidermal junction

Question 8

What is the type of collagen in the dermal epidermal junction

Answer 8

Type 4 collagen

Treat it as sth like basal lamina

Question 9

what are the 2 major types of collagen in dermis

Answer 9

Type 1

Type 3

Question 10

Name a type of polysaccharide that is always present in dermis

Answer 10

Hyaluronic acid

Question 11

Name 2 major components of dermis

Answer 11

Matrix

Ground Substance

Question 12

What is the major type of tissue in subcutis

Answer 12

Adipose tissue

Question 13

Name 4 components of pilosebaceous unit

Answer 13

Hair follicle
Sebaceous gland
Eccrine sweat gland
Apocrine sweat gland

Question 14

Name the disease that is caused by blockage of pilosebaceous units

Answer 14

Acne Vulgaris

Question 15

What is the type of hair in scalp

What is the size of this type of hair follicles

Answer 15

Terminal Hair

Large Hair Follicle

Question 16

What is the type of hair in forehead

What is the size of this type of hair follicles

Answer 16

Vellus Hair

Small Hair Follicle

Question 17

Why is the forehead more oily than other parts

Answer 17

Large Sebaceous glands

Question 18

The number of hair follicles change during your lifetime

True or false

Answer 18

False

Question 19

The number of hair follicles doesn’t change during your lifetime. Then why would you ‘lose hair’?
What is this phenomenon

Answer 19

More terminal hair is converted to vellus hair

Androgenetic alopecia

Question 20

Name the 3 stages of hair growth, and what r they

Answer 20

Anagen- Active growth
Catagen- Regressing
Telogen- Rest or Quiescent

Question 21

How many hair follicles does humans have on average?

Answer 21

100000

Question 22

What is called when physical or physiological stress causes 70% of hair to enter telogen phase prematurely

Answer 22

Telogen effluvium

Question 23

Name the 2 types of skin

Answer 23

Glabrous skin

hair-bearing skin

Question 24

Compare the Glabrous skin and hair-bearing skin

• Hair follicles
• Sebaceous glands
• Encapsulated sense organs
• Stratum corneum

Answer 24

Glabrous skin VS Hair-bearing skin
Hair follicles: No VS Yes
Sebaceous glands: No VS Yes
Encapsulated sense organs: Yes VS No
Glabrous skin has very thick stratum corneum

Question 25

Which type of sweat glands produce more lipid-rich secretion of sweat

Answer 25

Apocrine Sweat Gland

Rmb in CPRS you have Apo B-48 on VLDLs…

Question 26

Which type of sweat gland is responsible for thermoregulatory sweating

Answer 26

Eccrine sweat gland

Question 27

Skin functions as a mechanical barrier because there are __________________ bonds in stratum corneum

Answer 27

Skin functions as a mechanical barrier because there are Glutamyl-lysyl isodipeptide bonds in stratum corneum

Question 28

Which cell type is responsible for UV absorption and production of melanin

Answer 28

Melanocytes

Question 29

Vitamin D3 (Cholecalciferol) is produced from _______ upon sunlight exposure

Answer 29

Cholesterol

Question 30

Skin is responsible for sensation. Name 2 types of specialized sensory receptors for this

Answer 30

Merkel’s receptors

Meissner’s corpuscles