IASM 26: Skin Flashcards
What is the largest organ in human body
Skin
What are the 3 layers of skin
Epidermis
Dermis
Subcutis
Main cell type of Epidermis?
Keratinocytes
Name 1 feature of the epidermis layer
Stratified
There are 4 layers in the Epidermis layer, arrange it from the top to the bottom
Basale, Corneum, Granulosum, Spinosum
Corneum
Granulosum
Spinosum
Basale
What are the 2 major components of Dermal-epidermal junction
Protein
Glycoprotein
The basement membrane between epidermis and dermis is also called
Dermal epidermal junction
What is the type of collagen in the dermal epidermal junction
Type 4 collagen
Treat it as sth like basal lamina
what are the 2 major types of collagen in dermis
Type 1
Type 3
Name a type of polysaccharide that is always present in dermis
Hyaluronic acid
Name 2 major components of dermis
Matrix
Ground Substance
What is the major type of tissue in subcutis
Adipose tissue
Name 4 components of pilosebaceous unit
Hair follicle
Sebaceous gland
Eccrine sweat gland
Apocrine sweat gland
Name the disease that is caused by blockage of pilosebaceous units
Acne Vulgaris
What is the type of hair in scalp
What is the size of this type of hair follicles
Terminal Hair
Large Hair Follicle
What is the type of hair in forehead
What is the size of this type of hair follicles
Vellus Hair
Small Hair Follicle
Why is the forehead more oily than other parts
Large Sebaceous glands
The number of hair follicles change during your lifetime
True or false
False
The number of hair follicles doesn’t change during your lifetime. Then why would you ‘lose hair’?
What is this phenomenon
More terminal hair is converted to vellus hair
Androgenetic alopecia
Name the 3 stages of hair growth, and what r they
Anagen- Active growth
Catagen- Regressing
Telogen- Rest or Quiescent
How many hair follicles does humans have on average?
100000
What is called when physical or physiological stress causes 70% of hair to enter telogen phase prematurely
Telogen effluvium
Name the 2 types of skin
Glabrous skin
hair-bearing skin
Compare the Glabrous skin and hair-bearing skin
- Hair follicles
- Sebaceous glands
- Encapsulated sense organs
- Stratum corneum
Glabrous skin VS Hair-bearing skin Hair follicles: No VS Yes Sebaceous glands: No VS Yes Encapsulated sense organs: Yes VS No Glabrous skin has very thick stratum corneum
Which type of sweat glands produce more lipid-rich secretion of sweat
Apocrine Sweat Gland
Rmb in CPRS you have Apo B-48 on VLDLs…
Which type of sweat gland is responsible for thermoregulatory sweating
Eccrine sweat gland
Skin functions as a mechanical barrier because there are __________________ bonds in stratum corneum
Skin functions as a mechanical barrier because there are Glutamyl-lysyl isodipeptide bonds in stratum corneum
Which cell type is responsible for UV absorption and production of melanin
Melanocytes
Vitamin D3 (Cholecalciferol) is produced from _______ upon sunlight exposure
Cholesterol
Skin is responsible for sensation. Name 2 types of specialized sensory receptors for this
Merkel’s receptors
Meissner’s corpuscles
