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MBBS IASM > IASM 24: Cell Membrane > Flashcards

IASM 24: Cell Membrane Flashcards

1
Q

What is the innermembrane called in mitochondria

A

Cristae

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2
Q

There are circular DNA in the mitochondria. Where are most of the proteins for oxidative phosphorylation synthesized?

A

Nucleus

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3
Q

What is the curved membrane of Rough ER called?

A

Cisternae

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4
Q

What is the function of Smooth ER in Testis

A

Steroid hormone production

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5
Q

What is the function of Smooth ER in hepatocytes

A

Detoxification

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6
Q

What is the function of Smooth ER in striated muscle cells

A

Storage of Calcium ions

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7
Q

In Golgi Apparatus: Entry face is called _____ face; exit face is called _____ face

A

Entry: Cis face
Exit: Trans face

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8
Q

What is the significance of Golgi to the proteins?

A

Proteins get more mature in Golgi Apparatus

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9
Q

The layers in Golgi are interconnected

True or False

A

False

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10
Q

The contents from Golgi is transferred to the cell membrane through ________ with the aid of _______

A

Secretory Vesicle; Cytoskeleton

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11
Q

Where is lysosome being formed

A

In the Golgi Apparatus

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12
Q

Nucleus is _____ in H&E Staining

Eosinophilic or Basophilic

A

Basophilic

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13
Q

Which 5 chromosomes encodes rRNAs

A

13 14 15 21 22

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14
Q

Where is the site of rRNA synthesis

A

Nucleolus

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15
Q

For dark regions of the DNA, which type of chromatin is it? Is it used for gene transcription? Is it packed or lose?
For pale regions of the DNA, which type of chromatin is it? Is it used for gene transcription? Is it packed or lose?

A

(DH)
Dark; Heterochromatin; Compacted DNA; No gene transcription
Light; Eurochromatin; Loosely packed DNA; Yes gene transcription

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16
Q

What are the 3 types of cytoskeleton and their respective lengths?

A

Microfilament (<10nm)
Intermediate Filament (~10nm)
Microtubules (>10nm)

17
Q

Name 1 type of microfilament in cells

A

Actin

18
Q

Which substance is responsible for cell crawling and cell protrusion

A

Actin

19
Q

Which substance is responsible for formation of microvilli

A

Actin

20
Q

Which substance is responsible during cytokinesis and dividing the cell into 2 daughter cells?

A

Actin

21
Q

Name 5 Intermediate Filaments

A 
Keratin
Vimentin
Desmin
Neurofilament
Glial filament
22
Q

Where can you find keratin

A

Epithelial cells

23
Q

Where can you find vimentin

A

fibroblasts

24
Q

Where can you find desmin

A

Smooth muscle cells

25
Q

Where can you find neurofilaments

A

neurones

26
Q

Where can you find glial filments

A

glial cells

27
Q

During the transformation from epithelial cells to mesenchymal cells

There is down regulation of _____ and up regulation of _______

A

Down: Keratin
Up: Vimentin

28
Q

Are there microtubules in RBCs

A

No

29
Q

For microtubules, the centrosome is formed by ___ centrioles.
Each centrioles formed by ______ (number + something) of microtubules, total _____ microtubules.

A

For microtubules, the centrosome is formed by 2 centrioles.

Each centrioles formed by 9 triplet of microtubules, total 27 microtubules.

30
Q

Microtubule instability: Constant polymerization and depolymerization of microtubules. The Positive end ________ and the negative end _______.

A

Microtubule instability: Constant polymerization and depolymerization of microtubules. The Positive end elongates and the negative end shortens.

31
Q

Two molecules responsible for the transport of organelles and macromolecules by microtubules. Name them

A

Kinesin

Dynein

32
Q

Direction of transport of materials of
Kinesin
Dynein

A

Kinesin: From negative to positive end
Dynein: From positive to negative end

33
Q

Ciliary and flagella movements require ______.
It is formed by ________ (Number + something) of microtubules.
When ______ moves, it facilitates the beating action of cilia.

A

Ciliary and flagella movements require Axoneme. It is formed by 9 duplets of microtubules. When dyenin moves, it facilitates the beating action of cilia.

34
Q

What are located at the base of cilia and flagella for the formation of microtubules?

A

Basal Bodies

35
Q

____ and _____ tubulins polymerize to form microtubules

_____ tubulins in centrosomes organize the formation of spindle fibres

A

Alpha and Beta tubulins polymerize to form microtubules

Gamma tubulins in centrosomes organize the formation of spindle fibres

36
Q

Which component is necessary in breaking down long chain fatty acids by beta oxidation?

A

Peroxisomes

37
Q

In prophase, what happens

A

Condensed chromosomes

38
Q

In prometaphse, what happens

A

Breakdown of the nuclear membrane

MBBS IASM (46 decks)

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