host and microbiome Flashcards

1
Q

what is genome

A
  • the genetic material of animals, plants and bacteria consists of DNA
  • the genome includes both the genes and the non-coding DNA
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2
Q

what is meant by microbiome

A

the combined genetic material of the microorganisms in a particular environment on a population level

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3
Q

what is the role of the microbiome and its interaction with the host

A
  • microbiome reflects the host and their biology
  • roles in digestion, immune system, protection against pathogens, metabolism, behaviour
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4
Q

what is the role of the microbiome in gut health and disease

A
  • the diversity and abundance of microbes will influence energy balance, gut motility, inflammatory tone, mucosal integrity, appetite and signalling
  • can also negatively influence the gut barrier, promoting inflammation
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