Heme System Flashcards
The _____ ______ produces blood cells.
bone marrow
These cells carry oxygen.
RBC’s
Platelet plug formation.
Thrombocytes (Platelets)
secrete toxins to fight all pathogens.
Neutrophils (WBC)
Fight parasite worms and elevate allergic response.
Eosinophils ( WBC)
Release histamine to increase inflammatory response.
Basophils (WBC)
Adaptive immune response cells. (T cells, B cells, Memory cells)
Lymphocytes (WBC)
recognize infections and fight them off. (antigen presenting cells)
Monocytes
an inherited protein attached to the surface of red blood cells.
Rh factor
Rh positive can receive _____ or ______ blood.
Positive or negative
Rh negative can ONLY receive ______ blood.
negative
AB can receive blood from _______.
everyone
another name for hemostasis is ______.
clotting
Type O is the ______ _______.
universal donor
There two pathways to blood clotting _______ and _______.
intrinsic and extrinsic
Intrinsic blood clotting is trigged by ____ ___ ____ _____.
changes in the blood. (platelet aggregation)
Extrensic clotting is triggered by?
Something outside the blood vessels. (trauma)
You need _____ to clot.
Ca
What are the 3 heme accessory organs?
- kidneys
- spleen
- liver
The kidneys stimulate the production of _________.
erythrocytes
The spleen controls _______ production.
spleen controls thrombocyte production.
The liver helps with the ________ factor.
clotting
Name 3 anticoagulants
- Heparin
- Warfarin
- Aspirin
Enoxaprin is also called?
LMW Heparin
Clopidogrel (Plavix) is a _______ drug.
antiplatelet
Apixaban (Eliquis) is a ______.
anticoagulant
if a patient has a clot Heparin will ____ ______ ______ _____ ______?
Not get rid of it.
The end result of heparin is to?
slows down clotting
Heparin is used to prevent clots in patients with ______, ________, _______.
strokes, chronic a-fib, and post-op.
Clients on a heparin drip have aPTT levels drawn q___ - ____ hours to titrate the drip.
4-6
Therapeutic aPTT: _____ - ______x normal.
1.5-2x (how long you want the blood to take to clot)
Biggest side effect to monitor with Heparin is _______.
bleeding
Name 4 signs x symptoms of bleeding from heparin.
- Hematuria (pink tinged sputum)
- Hematemesis (bloody vomitus)
- Bruising
- H&Hct (decreased)
The antidote to heparin is ______ ______.
protamine sulfate
HITT is a complication of ______ therapy.
Heparin
HIIT usually occurs ______ - _______ days after Heparin exposure.
5-10 days
If there is an unexplained _____ _____ in any client on heparin suspect HIIT.
platelet drop
Chest pain, Chills, Dyspnea, and fever are clinical manifestations of ______.
HIIT
What is the treatment of HIIT?
Discontinue ALL heparin and start a different coagulant.
Name 3 NC’s of LMW heparin.
- Always give SC
- Can be used during pregnancy (the only one)
- May have cultural/religious implications.