Exam 3 Lec Notes Contd... Again Flashcards
thyroid gland: two lobes on either side of the …
trachea
parafollicular cells are next to …
follicular cells
thyroid hormone helps maintain proper … in adults
sexual function
thyroglobulin is produced by … cells
follicular
iodide is transferred from blood side of cell and brought into …
colloid space
peroxidase …
oxidizes
T3 and T4 are … across membrane and into bloodstream
exocytosed
thyroglobulin is … –> moved through ER into …into … that are transported to the colloid lumen
thyroid precursor; Golgi; vesicles
iodide is actively transported into cell and to … –> when in colloid itself, peroxidase oxidizes it to iodine, which is then attached to tyrosines that are a part of ….
If 2 iodines are attached it forms …, if 1 iodine is attached it forms …
colloidal lumen;
thyroglobulin;
diiodotyrosine;
monoiodotyrosine
MIT and DIT link together in a … fashion to form T3 and T4 (2 MITs never link up though - we don’t get a …)
random; T2
… in heavy amounts in bloodstream to carry thyroid hormones
thyroxine-binding globulins
TRH overcomes negative feedback during pregnancy because these women need high metabolism because a lot of nutrients are needed for …
proper fetal development
TRH process for cold isn’t really effective in humans - more of an animal thing
humans generate body heat by … (through …)
overworking skeletal muscle system; exertion
cretinism: greatly reduced …
stature
Graves’ disease: metabolism is constantly turned on, which leaves you …, unable to …, constantly …, can’t … no matter how much you eat
similar side effects people doing amphetamines
incredibly unhealthy
jittery; sleep; nervous; put on weight
goiter: caused by the thyroid gland itself becoming … due to the fact that it’s desperately … –> swells to increase its … such that, even if there are trace amounts of what its looking for in the blood, it has higher chances of being able to absorb them
swollen;
seeking iodide;
surface area
… is one of the diagnostic conditions that a physician can use to diagnose Graves’ disease
eyes bulging out of the head