Exam 3 Lec Notes Contd... Again Flashcards

1
Q

thyroid gland: two lobes on either side of the …

A

trachea

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2
Q

parafollicular cells are next to …

A

follicular cells

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3
Q

thyroid hormone helps maintain proper … in adults

A

sexual function

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4
Q

thyroglobulin is produced by … cells

A

follicular

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5
Q

iodide is transferred from blood side of cell and brought into …

A

colloid space

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6
Q

peroxidase …

A

oxidizes

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7
Q

T3 and T4 are … across membrane and into bloodstream

A

exocytosed

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8
Q

thyroglobulin is … –> moved through ER into …into … that are transported to the colloid lumen

A

thyroid precursor; Golgi; vesicles

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9
Q

iodide is actively transported into cell and to … –> when in colloid itself, peroxidase oxidizes it to iodine, which is then attached to tyrosines that are a part of ….
If 2 iodines are attached it forms …, if 1 iodine is attached it forms …

A

colloidal lumen;
thyroglobulin;
diiodotyrosine;
monoiodotyrosine

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10
Q

MIT and DIT link together in a … fashion to form T3 and T4 (2 MITs never link up though - we don’t get a …)

A

random; T2

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11
Q

… in heavy amounts in bloodstream to carry thyroid hormones

A

thyroxine-binding globulins

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12
Q

TRH overcomes negative feedback during pregnancy because these women need high metabolism because a lot of nutrients are needed for …

A

proper fetal development

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13
Q

TRH process for cold isn’t really effective in humans - more of an animal thing
humans generate body heat by … (through …)

A

overworking skeletal muscle system; exertion

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14
Q

cretinism: greatly reduced …

A

stature

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15
Q

Graves’ disease: metabolism is constantly turned on, which leaves you …, unable to …, constantly …, can’t … no matter how much you eat
similar side effects people doing amphetamines
incredibly unhealthy

A

jittery; sleep; nervous; put on weight

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16
Q

goiter: caused by the thyroid gland itself becoming … due to the fact that it’s desperately … –> swells to increase its … such that, even if there are trace amounts of what its looking for in the blood, it has higher chances of being able to absorb them

A

swollen;
seeking iodide;
surface area

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17
Q

… is one of the diagnostic conditions that a physician can use to diagnose Graves’ disease

A

eyes bulging out of the head

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18
Q

eyes bulging occurs in Graves’ because it’s an autoimmune disease in which body produces number of different antibodies, some of which bind …, causing those muscles to build up … Because orbitals of eyes are made out of bone, there’s nowhere to expand but out so eyes are getting pushed out of eye sockets

A

muscles in the eyes;

scar tissue

19
Q

in other animals, calcitonin is antagonistic to …

A

PTH

20
Q

2 types of cells in bones: … and …

A

osteoclasts; osteoblasts

21
Q

… break apart bone- digest it to free up calcium which enters bloodstream
calcitonin … this activity

A

osteoclasts

inhibits

22
Q

… follow closely behind osteoclasts and rebuild bone that was broken down
calcitonin … this activity

A

osteoblasts;

stimulates

23
Q

vitamin D increases … in the …

A

absorption of calcium;

intestines

24
Q

…. –> deformation of bones that occurs when hyperparathyroidism occurs during puberty

A

bows and bends

25
Q

… responsible for proper parathyroid cell function

A

Mg

26
Q

… during hypoparathyroidism

A

misfiring of muscles and nervous tissue

27
Q

unlike all of the other endocrine tissue we talk about, the parathyroid glands don’t have to be located on the thyroid –> parathyroid glands can “pop off” of thyroid and …, oftentimes to the …

A

travel elsewhere;

lungs

28
Q

… isn’t actually glandular tissue

A

adrenal medulla

29
Q

sodium important for regulation of … in bloodstream

A

water

30
Q

… of neural and muscular tissues can be outcome of aldosteronism

A

mis/nonfiring

31
Q

if no glucose in liver – haven’t eaten in at least … –> indicates to body that one is under stress and … is released

A

a day;

cortisol

32
Q

cortisol, like all stress hormones/steroids inhibits immune system and increases risk of …

A

opportunistic infections

33
Q

want adrenal medulla response to be brief, otherwise constant release of epi will …

A

exhaust body

34
Q

melatonin can … body system –> decreasing body temps, suppressing …

A

slow;

appetite

35
Q

in order for sugar to enter cells, there are … on plasma membrane which transport it across –> insulin works through these

A

glucose transporters

36
Q

insulin stimulates a number of metabolic processes which is why it influences …

A

neuronal development

37
Q

…. of liver, kidney, and brain is why these tissues don’t need insulin

A

hight metabolism

38
Q

insulin is all about … for … use and glucagon is for … now

A

storing energy; later;

using stored energy

39
Q

type 1 DM - …, body… in pancreas

A

autoimmune;

destroys beta cells

40
Q

Type 2 DM- body has been exposed to such high levels of sugar that body doesn’t …
…of insulin receptors occur

A

respond to insulin;

downregulation

41
Q

ketoacidosis can be fatal in … only (not normal people)

A

diabetics

42
Q

polyphagia in diabetes never leads to … because body can’t take up glucose

A

weight gain

43
Q

leptin is what allows us to know we’re … –> lack of this hormone leads to …

A

full;

overeating