Exam 2 Info - Slides Contd Flashcards
blood vessels: delivery system of dynamic structures that begins and ends at heart
arteries: carry blood … heart; oxygenated except for … and …
capillaries: contact …; directly serve cellular needs
veins: carry blood … heart
away from; pulmonary circulation; umbilical vessels of fetus;
tissue cells;
toward
(structure of blood vessel walls) …: central blood-containing space
lumen
(structure of blood vessel walls) three wall layers in arteries and veins: …, …, and …
tunica intima; tunica media; tunica externa
(structure of blood vessel walls) capillaries: … with sparse …
endothelium; basal lamina
(tunics) tunica intima:
… lines lumen of all vessels –> continuous with .., slick surface reduces …
endothelium; endocardium; friction
(tunics) tunica intima:
… in vessels larger than 1 mm; connective tissue basement membrane
subendothelial layer
(tunics) tunica media:
… and sheets of …
sympathetic vasomotor nerve fibers control … and … of vessels –> influence blood .. and …
smooth muscle; elastin;
vasoconstriction; vasodilation;
flow; pressure
(tunics) tunica externa (tunica adventitia):
… protect and reinforce; anchor to surrounding structures
contains …, …
… of larger vessels nourishes external layer
collage fibers;
nerve fibers; lymphatic vessels;
vasa vasorum
vessels vary in …, …, …, …
length; diameter; wall thickness; tissue makeup
(arterial system: elastic arteries) large thick-walled arteries with … in all three tunics
… and its major branches
large lumen offers …
elastin;
aorta;
low-resistance
(arterial system: elastic arteries) inactive in …
act as … - expand and recoil as blood ejected from heart – smooth pressure downstream
vasoconstriction;
pressure reservoirs
(arterial system: muscular arteries) … to elastic arteries – deliver blood to …
thick … with more smooth muscle
active in …
distal; body organs;
tunica media;
vasoconstriction
(arterial system: arterioles) smallest arteries
lead to …
control flow into these regions via … and …
capillary beds; vasodilation; vasoconstriction
(capillaries) microscopic blood vessels
walls of thin tunica intima –> in smallest … forms entire circumference
… help stabilize their walls and control permeability
diameter allows only … to pass at a time
oen cel;
pericytes;
single RBC
(capillaries) in all tissues except for …, …, … and … of eye
cartilage; epithelia; cornea; lens
(capillaries) provide … to almost every cell
functions:
exchange of …, …, …, …, etc., between blood and interstitial fluid
direct access;
gases; nutrients; wastes; hormones;
(capillaries) three structural types:
…. capillaries
… capillaries
… capillaries (…)
continuous;
fenestrated;
sinusoid; sinusoids
(continuous capillaries) abundant in skin and muscles:
… connect endothelial cells
… allow passage of fluids and small solutes
tight junctions;
intercellular clefts
(continuous capillaries) continuous capillaries of brain unique:
tight junctions are …, forming …
complete; blood-brain barrier
(fenestrated capillaries) some endothelial cells contain … (…)
more … than continuous capillaries
pores; fenestrations;
permeable
(fenestrated capillaries) function in … or … formation (small intestines, endocrine glands, and kidneys)
absorption; filtrate
(sinusoid capillaries) fewer …; usually …; larger …; large …
tight junctions; fenestrated; intercellular clefts; lumens
(sinusoid capillaries) blood flow … — allows …
large molecules and blood cells pass between blood and surrounding tissues
sluggish; modification
(sinusoid capillaries) found only in the …, …, …, …
… in lining to destroy bacteria
liver; bone marrow; spleen; adrenal medulla;
macrophages
(capillary beds) microcirculation:
interwoven networks of capillaries between … and …
terminal arteriole –> …
arterioles; venules;
metarteriole
(capillary beds) microcirculation:
metarteriole continuous with … (intermediate between capillary and venule)
thoroughfare channel
(capillary beds) thoroughfare channel –> … that drains bed
postcapillary venule
(capillary beds) … (….-… channel): directly connects terminal arteriole and postcapillary venule
vascular shunt; metarteriole-thoroughfare
(capillary beds) …: 10 to 100 exchange vessels per capillary bed
branch off metarteriole or terminal arteriole
true capillaries
true capillaries normally branch from … and return to …
metarteriole; thoroughfare channel
… regulate blood flow into true capillaries – blood may go into true capillaries or to shunt
regulated by … and …
precapillary sphincters; local chemical conditions; vasomotor nerves
sphincters open – blood flows through …
sphincters closed - blood flows through … channel and bypasses true capillaries
true capillaries;
metarteriole-thoroughfare
(venules) formed when capillary beds … –> smallest postcapillary venules; very …; allow … and … into tissues
consist of … and a few …
unite;
porous; fluids; WBCs;
endothelium; pericytes
(venules) larger venules have one or two layers of
smooth muscle cells
(veins) formed when venules converge
have … walls, … lumens compared with corresponding arteries
blood pressure … than in arteries
thinner; larger;
lower
(veins) thin …; thick … of collagen fibers and elastic networks
called … (…); contain up to 65% of blood supply
tunica media; tunica externa;
capacitance vessels; blood reservoirs
(veins) adaptations ensure return of blood to heart despite low pressure:
large diameter lumens offer …
… prevent backflow of blood –> most abundant in veins of….
…: flattened veins with extremely thin walls (e.g. coronary sinus of the heart and dural sinuses of the brain)
little resistance;
venous valves; limbs;
venous sinuses
…: volume of blood flowing through vessel, organ, or entire circulation in given period
blood flow
blood flow:
measured as …
equivalent to … for entire vascular system
relatively … when at rest
varies widely through individual organs, based on needs
ml/min;
cardiac output;
constant
blood pressure:
… per … exerted on wall of blood vessel by blood
expressed in …
measured as … in large arteries near heart
force; unit area;
mm Hg;
systemic arterial BP
blood pressure:
… provides driving force that keeps blood moving from higher to lower pressure areas
pressure gradient
resistance (peripheral resistance): …
measure of amount of … blood encounters with vessel walls, generally in peripheral (…) circulation
opposition to flow; friction; systemic
three important sources of resistance:
blood …
total …
blood vessel …
viscosity;
blood vessel length;
diameter
(resistance) factors that remain relatively constant:
…: the “stickiness” of blood due to formed elements and plasma proteins
…
blood viscosity;
blood vessel length
(resistance) increased viscosity = … resistance
longer vessel = … encountered
increased; greater resistance
(resistance) … is greatest influence on resistance
frequent changes alter …
varies inversely with … of vessel radius
blood vessel diameter;
peripheral resistance;
fourth power
(resistance) … major determinants of peripheral resistance
small-diameter arterioles
(resistance) abrupt changes in diameter or fatty plaques from … dramatically increase resistance –> disrupt … and cause …
… equals increased resistance
atherosclerosis;
laminar flow; turbulent flow;
irregular fluid motion
(resistance) blood flow (F) directly proportional to …
if this latter variable increases, blood flow …
pressure gradient (delta P); speeds up
(resistance) blood flow inversely proportional to …
if the latter variable increases, blood flow …
F = …
peripheral resistance; decreases;
delta P/ R
(resistance) R more important in influencing local blood flow because easily changed by altering …
blood vessel diameter
systemic blood pressure:
… of heart generates blood flow
pressure results when flow is …
pumping action;
opposed by resistance
systemic blood pressure: highest in ... ... throughout pathway 0 mm Hg in ... steepest drop occurs in ...
aorta;
declines;
right atrium;
arterioles
arterial blood pressure: reflects two factors of arteries close to heart: ... (.../...) ... forced into them at any time blood pressure near heart is ...
elasticity; compliance; distensibility;
volume of blood;
pulsatile
arterial blood pressure:
systolic pressure: pressure exerted in … during …
averages … mm Hg in normal adult
aorta; ventricular contraction; 120
arterial blood pressure:
…: lowest level of aortic pressure
diastolic pressure
arterial blood pressure:
… = difference between systolic and diastolic pressure
throbbing of arteries (…)
pulse pressure;
pulse