embryology 3: development of midline structures Flashcards
where does the pituitary gland sit?
in the pituitary fossa of the sella turcica (deepest part of sphenoid bone - middle cranial fossa)
what is the pituitary gland?
a functional connection with the cerebellum and forebrain
what are the anatomical relations of the pituitary gland?
inferior to hypothalamus
hypophysis (hypothesis) + hypophysis cerebri (pituitary) - joined together by pituitary stalk
what is the posterior lobe of pituitary gland composed of?
neuroectoderm (collection of neurons)
neurohypophysis - modified neural tissue
where does the posterior lobe of the pituitary gland originate from?
infundibulum of the forebrain (downward outgrowth of diencephalon which grows toward the roof of the pharynx - CAUDALly)
where does the pituitary stalk originate from?
posterior lobe
what does the anterior lobe of the pituitary gland form from?
outpocketing of ectoderm of the stomatoderm called RATHKE’s POUCH
(stomatoderm forms body organs, and the pituitary gland is a glandular tissue)
where does the evagination of Rathke’s pouch for anterior pituitary come from?
roof of oropharynx primordial and grows DORSALly towards the developing brain
what happens to Rathke’s pouch?
pinches off from the ectoderm (outpocketing from stomatoderm) and becomes separated
what functionally links the anterior lobe of the hypothalamus and posterior pituitary lobe?
hypophyseal portal system
no need to enter systemic circulation
summary of origin of anterior and posterior lobes of the pituitary gland
anterior: endocrine organ (stomatoderm), Rathke’s pouch (outpocketing of ectoderm), grows up dorsally from roof of oropharynx
posterior: neuroectoderm (neural tissue), from infundibulum of forebrain, grows caudally towards roof of oropharynx
both linked by hypophyseal portal system
what happens after the anterior and posterior lobes grows towards each other?
they sit in the developing sphenoid bone as it ossifies to form the sella turcica (pituitary fossa)
where does the tongue receive contributions from?
all 5 arches
where does the tongue lie?
partly in the oral cavity and partly in the (oro)pharynx
what is the tongue comprised of?
extrinsic and intrinsic muscles
highly mobile, attached to floor of mouth via lingual frenulum
how is the tongue divided functionally?
anterior 2/3 and posterior 1/3
separated by sulcus terminalis with foramen cecum forming apex
when does the primordial of the tongue appear?
at the same time as the palate begins to form (palatal shelves of maxillary prominence)
what forms the pharyngeal floor?
from the fusion of ventral parts of the pharyngeal arches and pouches (endoderm)
what happens as the pharynx floor develops?
the tongue primordia receives a component from each of the pharyngeal arches where they meet in the midline
what is the tongue formed from?
2 lateral swellings (Ph A 1)
3 median swellings (PhA 1-4)