Chapter 5: The Pancreas Flashcards
the cells of the pancreas that carry out the exocrine function and, therefore, produce amylase, lipase, sodium bicarbonate, and other digestive enzymes
acinar cells
congenital anomaly of the pancreas that results in the maldevelopment of the pancreas in which the most ventral part of the pancreas encases the duodenum and may consequently lead to duodenal obstruction
annular pancreas
the recurring destruction of the pancreatic tissue that results in atrophy, fibrosis with scarring, and the development of calcification within the gland
chronic pancreatitis
inherited disorder that can affect the lungs, liver, pancreas, and other organs; this disorder changes how the body creates mucus and sweats
cystic fibrosis
coexisting enlargement of the common bile duct and pancreatic duct
double-duct sign
the accessory duct of the pancreas
duct of Santorini
the main pancreatic duct
duct of Wirsung
the first segment of the small intestine
duodenum
endoscopic procedure that utilize flouroscopy (radiographic imaging) to evaluate the biliary tree and pancreas
endoscopic retrograde cholangiopancreatography
form of pancreatitis associated with gallstones and pancreatic duct obstruction
gallstone pancreatitis
an islet cell tumor found within the cells of the pancreas that may produce an abundance of gastrin
gastrinoma
form of pancreatitis associated with bleeding within or around the pancreas
hemorrhagic pancreatitis
elevated amylase
hyperamylasemia
the presence of elevated parathyroid hormone
hyperparathyroidism
bowel obstruction caused by the lack of normal peristalsis
ileus
an islet cell tumor found within the beta cells of the pancreas that may produce an abundance of insulin
insulinoma
most common form of pancreatitis; associated with inflammation of the pancreas and peripancreatic tissue without necrosis
interstitial edematous pancreatitis
tumor found within the islets of Langerhans of the pancreas
islet cell tumors
small islands of tissue found within the pancreas that produce insulin and glucagon
islets of Langerhands
a peritoneal cavity located between the stomach and the pancreas where fluid can accumulate
lesser sac
death of tissue
necrosis
severe form of acute pancreatitis in which there is death of the pancreatic tissue
necrotizing pancreatitis
the most common form of pancreatic malignancy, typically found within the head of the pancreas
pancreatic adenocarcinoma
congenital anomaly of the pancreas that results in a shortened main pancreatic duct that only works to drain the pancreatic head and not the entire pancreas
pancreatic divisum
the surgical procedure in which the head of the pancreas, the gallbladder, some of the bile ducts, and the proximal duodenum are removed because of a malignant pancreatic neoplasm; also referred to as the Whipple procedure
pancreaticduodenectomy
a cyst surrounded by fibrous tissue that consists of pancreatic enzymes that have leaked from the pancrea
pancreatic pseudocyst
fatty infiltration of the pancreas; may be classified as alcoholic or nonalcoholic; may also be referred to as a fatty pancreas
pancreatic steatosis
the peripancreatic fluid collection that results from inflammation of the pancreas
phlegmon
a posteromedial extension of the pancreatic head
uncinate process
a hereditary disease that includes the development of cysts within the pancreas and other organs
von Hippel-Lindau disease
Whipple procedure
pancreaticoduodectonomy
a group of clinical indicators of a functional insulinoma; includes hypoglycemia, low fasting glucose, and relief with intravenous glucose administration
Whipple triad
the syndrome that includes an excessive secretion of acid by the stomach caused by the presence of a functional gastrinoma within the pancreas`
Zollinger-Ellison syndrome
digests carbohydrates and converts starch to sugar
amylase
digests fat and converts fats to fatty acids and glycerol
lipase
neutralizes stomach acid
sodium bicarbonate
breaks down proteins
trypsin, chymotripsin, and caroboxypolypeptides
glucagon- promotes the release of glucose by the liver (increases blood sugar level)
alpha cells
insulin- stimulates the body’s use of glucagon
beta cells
somatostatin- restrains insulin and glucose levels
Delta cells
The pancreatic head is located right lateral to the _______
SMV
The pancreatic head is ____ to the IVC and _____ to the portal vein
anterior
posterior
The unicinate process is ______ to SMV
posterior
The uncinate process is anterior to the _____
aorta
The pancreatic neck is anterior to the ______
portal confluence
The pancreatic tail is marked by the posterior border of the ____
splenic vein`
pancreatitis associated with gallstones and concurrent obstruction of the pancreatic duct
gallstone pancreatitis
pancreatitis associated with bleeding in or around the pancreas; high rate or morbidity and mortality
hemorrhagic pancreas
Form of chronic pancreatitis that results from the body’s immune system attacking the pancreas
autoimmune pancreatitis
Uncommon form of chronic pancreatitis found in the head of the pancreas with associated inflammation of the CBD and second portion of the duodenum`
groove pancreatitis
Form of acute pancreatitis results in the necrosis of the pancreatic parenchyma and the tissue surrounding the pancreas; high rate of morbidity and mortality
Necrotizing pancreatitits
Most common form of acute pancreatitis; associated with inflammation of the pancreatic parenchyma and peripancreatic tissues; necrosis is not present
interstitial edematous pancreatitis
elevated amylase
elevated lipase
leukocytosis
elevated ALT and other liver function labs when biliary obstruction is present
abdominal pain
back pain
fever
nausea and vomiting
acute pancreatitis
pancreas may appear normal
diffusely, enlarged, hypoechoic pancreas (diffuse manifestation)
focal hypoechoic area within the pancreas (total manifestation)
unencapsulated anechoic fluid collection surrounding all or part of the pancreas (peripancreatic fluid)
pancreatic pseudocyst
abscess formation can occur
biliary obstruction may be present
acute pancreatitis
asymptomatic
persistent epigastric pain
jaundice
back pain
possible elevation in amylase or lipase (but they may remain normal)
possible elevation in ALP
anorexia
vomiting
weight loss
constipation
chronic pancreatitis
heterogenous, or hyperechoic, atrophic gland with poor margins
calcifications within the gland
pancreatic pseudocyst
dilated pancreatic duct
stone(s) within the pancreatic duct that may lead to biliary obstruction
possible portosplenic vein thrombosis
chronic pancreatitis
elevated amylase and/or lipase
loss of appetite
weight loss
jaundice
courvoisier gallbladder
epigastric pain
elevated ALP and, possibly, other liver function labs associated with biliary obstruction
History of cigarette smoking, diabetes mellitus, or chronic pancreatitis
Pancreatic Adenocarcinoma
hypoechoic mass in the head of the pancreas
dilated CBD and pancreatic duct (double-duct sign)
liver and other abdominal organs should be evaluated for possible metastasis
enlarged hydropic gallbladder
pancreatic adenocarcinoma
may be asymptomatic initially
epigastic pain
weight loss
palpable mass
jaundice
cystadenomas and cystadenocarcinoma
cystic mass
may actually appear solid and echogenic secondary to the small size of the cysts
serous cystadenoma
multilocular cystic masses that may contain mural nodules and calcifcations
there may be associated dilation of the pancreatic duct
mucinous cystadenoma and cystadenocarcinoma
hypoglycemia, low fasting glucose, and relief with intravenous glucose administration (Whipple triad)
Insulinoma islet cell tumor
Zollinger-Ellison syndrome
Gastrinoma islet cell tumor