Chapter 15 microbiology Flashcards

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1
Q

What immunity discriminates well between self and non self

A

adaptive

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2
Q

What immunity is enormously diverse

A

adaptive

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3
Q

Which immunity has the same response to each pathogen

A

innate

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4
Q

molecultes that are recognized by t cells or b cells

A

antigens

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5
Q

PAMP and antigens both do what

A

initiate immune response

recognized by receptors on leukocytes

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6
Q

What differs between PAMP and antigen

A

PAMP are part of innate immunity and on many pathogens

Antigens are part of adaptive immunity and have epitopes

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7
Q

What is the clonal selection theory stating

A

cell division and gene rearrangements form unique cell surface receptors that reside in the lymph node until antigen triggers it

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8
Q

In the clonal selection theory what happens to cell surface receptors that are recognized by self

A

they are eliminated

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9
Q

What will binding of antigen to a cell surface receptor trigger

A

clonal expansion and cytokines released to population

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10
Q

What are B cell clones called

A

plasma cells and memory b cells

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11
Q

What are MHC l receptors

A

recognize what is us and found on all cells but RBC

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12
Q

What are MHC ll receptors

A

found on APC’s and recognize antigen presenting cells

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13
Q

B cells have __________ on their surface

A

antibodies

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14
Q

When an antigen binds to the b cell end of antibody what does it trigger

A

b cell differentiation

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15
Q

antibody factories are _________ cells

A

plasma

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16
Q

long lived cells capable of quickly producing more effector cells in b cells are

A

memory b cells

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17
Q

B cells present the antigen on the surface of their cell, ___________–> induce further cytokine produciton and faciliate b cell differentiation

A

t cells recognize

18
Q

serum of blood containing specific antibodies

A

antiserum

19
Q

Primary response to antiserum

A

latent period

20
Q

Secondary response to antiserum

A

no latent period and faster

21
Q

What is the job of T helper cells

A

release cytokines

22
Q

what is the job of killer T cells

A

destroy nearby cells

23
Q

Unlike b cell receptors t cell receptors…

A

are small and not secreted

24
Q

What are APC

A

dendritic cells
macrophages
b cells

25
Q

What do t cells interact with

A

APC

26
Q

What do CD8 t cells do

A

recognize MHC ll and antigen and target cell for destruction

27
Q

What do CD4 helper t cellls do

A

trigger cytokine production

28
Q

What do CD4 t memory cells do

A

store in lymph nodes and protect against future encounters with the same antigen

29
Q

Where do b cell mature

A

bone marrow

30
Q

A high number of _____ cells circulate blood while ____ cells have low number

A

b; t

31
Q

acquired through the normal life experience

A

natural immunity

32
Q

e.g. of natural active immunity

A

develop own immunity

33
Q

e.g of passive active immunity

A

breast feeding

34
Q

produced purposefully through medical procedures

A

artificail immunity

35
Q

e.g. active artificial immunity

A

vaccine

36
Q

vaccine that uses inactivated virus with antigen

A

killed vaccines

37
Q

vaccine that uses live cells or viruses

A

attenuated vaccine

38
Q

vaccine that uses portions of virus or pathogens

A

acellular vaccine

39
Q

vaccine that uses portions of DNA

A

recomboniant vaccine

40
Q

Why do we need boosters

A

new strains evolve

re stimulate our immune system