BRDC

Question 1

What three things are needed for treatment success in any animal?

Answer 1

Cows defense, antibiotic and pathogen that can be overcome

Question 2

Which drug costs the most to treat BRDC and is used most often?

Answer 2

Draxxin

Question 3

When did micotyl come out?
When did all the drugs start to lose efficacy?

Answer 3

1992
2010

Question 4

What drug options were available in the dark ages?

Answer 4

Oxytetracycline, sulfa, spectomycin, gentamycin and chloramphenicol

Question 5

What occurred in the golden era of antibiotics?

Answer 5

Many new antibiotics were released and all were very eefective

Question 6

Where are we at currently with anitibiotics?

Answer 6

Rise of resistance and less effective

Question 7

What 3 things could be occurring if there is still death after treating herds?

Answer 7

Super bug, poor detection or antibiotic resistance

Question 8

How do you determine if there is timely disease recognition?

Answer 8

Go through records, some animals pulled should not have a fever (not pulling enough)

Question 9

Is multidrug resistance increasing?

Answer 9

Yes! (Ceftiofur still best)

Question 10

What bacteria is commonly seen as a super bug?

Answer 10

Mannheim Hemolytic

Question 10

Why is Mannheim a super bug?

Answer 10

Leukotoxin destroys WBC and makes inflammation even worse

Question 11

What kind of animals are more likely to struggle with this inspite of vaccination?

Answer 11

Stressed animals, weaned recently, castrated, branded/worked,

Question 12

When you suspect BRDC you should remember this is a multifactorial disease and always address what first?

Answer 12

Management and Environment

Question 13

What is metaphylaxis?

Answer 13

Preemptive treatment with antibiotics when you think that up to a third of the herd may acquire BRDC

Question 14

Which drugs can be used for metaphylaxis?

Answer 14

Any class: noromycin, exced, nuflor, baytril, mictoil, draxin, zactran or zuprevo

Question 15

If you need to treat a group of animals that have been treated metaphylaxis then what do you use?

Answer 15

A different drug than the one you used for metaphylaxis

Question 16

When should you consider using metaphylaxis?

Answer 16

expect more than 35% ill, expensive calves, substitute for time/labor

In outbreak: if 25% of calves treated in one day, 10% of the calves treated for 3 days in a row

Question 17

What type of bacteria is mycoplasma bovis and where does it like to be?

Answer 17

Gram positive, intracellular, no cell wall (never use beta lactam)

Question 18

What type of issues can mycoplasma bovis cause in a cow?

Answer 18

Pneumonia, Septic Joint or Ear Infection (bilateral droop)

Question 19

What are some clinical signs of mycoplasma pneumonia?

Answer 19

poor response to therapy, relapse in a week or month, multiple episodes, hacking cough, severe labored breathing, nasal discharge, lower tempts than other viral pathogens

Question 20

What are signs of a Septic joint from mycoplasma?

Answer 20

swelling in one or more legs, severely lame (can make them starve to death) , most will recover if given time (in joint capsule)

Question 21

What can you do to help a calf with BRDC get better?

Answer 21

Keep in small pen and have food and water close

Question 22

How do you treat mycoplasma joints?

Answer 22

antibiotic, NSAID, open abscess (no enter joint capsule)

Question 23

How do you treat Histophilus Somni?

Answer 23

1 gram CTC per 100lbs BW for 5 days
(not approved but never see again - P.multocida is approved so it ok)

Question 24

What are some clinical signs of H. Somni?

Answer 24

Respiratory, cardia, dull, just want to sleep

Question 25

What is TEME?

Answer 25

Thromboembolicmeningioencephalitis (common in northern feedlots)

Question 26

When should you stop treating a BRDC case?

Answer 26

After 3 failed attempts (very little lung tissue left)

Question 27

When should you switch antibiotics?

Answer 27

48 hours after choosing a treratment before switching (give time to work) or after the time that the drug should be working (post treatment interval)