BRDC Flashcards
What three things are needed for treatment success in any animal?
Cows defense, antibiotic and pathogen that can be overcome
Which drug costs the most to treat BRDC and is used most often?
Draxxin
When did micotyl come out?
When did all the drugs start to lose efficacy?
1992
2010
What drug options were available in the dark ages?
Oxytetracycline, sulfa, spectomycin, gentamycin and chloramphenicol
What occurred in the golden era of antibiotics?
Many new antibiotics were released and all were very eefective
Where are we at currently with anitibiotics?
Rise of resistance and less effective
What 3 things could be occurring if there is still death after treating herds?
Super bug, poor detection or antibiotic resistance
How do you determine if there is timely disease recognition?
Go through records, some animals pulled should not have a fever (not pulling enough)
Is multidrug resistance increasing?
Yes! (Ceftiofur still best)
What bacteria is commonly seen as a super bug?
Mannheim Hemolytic
Why is Mannheim a super bug?
Leukotoxin destroys WBC and makes inflammation even worse
What kind of animals are more likely to struggle with this inspite of vaccination?
Stressed animals, weaned recently, castrated, branded/worked,
When you suspect BRDC you should remember this is a multifactorial disease and always address what first?
Management and Environment
What is metaphylaxis?
Preemptive treatment with antibiotics when you think that up to a third of the herd may acquire BRDC
Which drugs can be used for metaphylaxis?
Any class: noromycin, exced, nuflor, baytril, mictoil, draxin, zactran or zuprevo
If you need to treat a group of animals that have been treated metaphylaxis then what do you use?
A different drug than the one you used for metaphylaxis
When should you consider using metaphylaxis?
expect more than 35% ill, expensive calves, substitute for time/labor
In outbreak: if 25% of calves treated in one day, 10% of the calves treated for 3 days in a row
What type of bacteria is mycoplasma bovis and where does it like to be?
Gram positive, intracellular, no cell wall (never use beta lactam)
What type of issues can mycoplasma bovis cause in a cow?
Pneumonia, Septic Joint or Ear Infection (bilateral droop)
What are some clinical signs of mycoplasma pneumonia?
poor response to therapy, relapse in a week or month, multiple episodes, hacking cough, severe labored breathing, nasal discharge, lower tempts than other viral pathogens
What are signs of a Septic joint from mycoplasma?
swelling in one or more legs, severely lame (can make them starve to death) , most will recover if given time (in joint capsule)
What can you do to help a calf with BRDC get better?
Keep in small pen and have food and water close
How do you treat mycoplasma joints?
antibiotic, NSAID, open abscess (no enter joint capsule)
How do you treat Histophilus Somni?
1 gram CTC per 100lbs BW for 5 days
(not approved but never see again - P.multocida is approved so it ok)
What are some clinical signs of H. Somni?
Respiratory, cardia, dull, just want to sleep
What is TEME?
Thromboembolicmeningioencephalitis (common in northern feedlots)
When should you stop treating a BRDC case?
After 3 failed attempts (very little lung tissue left)
When should you switch antibiotics?
48 hours after choosing a treratment before switching (give time to work) or after the time that the drug should be working (post treatment interval)
