blood 5; disorders of hemostasis Flashcards
vitamin k deficiency disorders include
liver disease
malabsorption syndromes
prothrombin turns into
thrombin
bruising for seemingly no reason
purpura
carries coagulation factor 8
von willebrand factor
stoppage of blood flow
hemostasis
thrombotic thrombocytopenic purpura
bacteria activates thrombosis; runs out of platelets and bleeds under skin (bruise)
plasmapheresis required
potentially fatal
white blood cells that live in tissue lifespan
3-5 days
bruising on bottoms of feet while crawling/walking
hemophilia
treatment is used so patient doesnt bleed out during surgery
prophylaxis
needed to form platelet plug
von willebrand factor
fibrinogen turns into
fibrin
average thrombocyte lifespan
8-9 days
antigen/antibody complex that causes platelet destruction
drug induced thrombocytopenia
angiogenesis
beginning of new vessels
happens immediately after injury
TTP =
thrombotic thrombocytopenic purpura
hypercoagulability can come from
increased platelet function
increase clotting factor activity
increased platelets and clotting factor
hypercoagulability
in blood coag, __ is required
vitamin K
fibrinolysis
destroys blood clots
x linked; coag defected
hemophilia
clot retraction/ drying out
clot restraction
intentional removal of blood by needle treatment
plasmapheresis
thrombocyte range
150K to 400K
serum is extracted in this stage of hemostasis
clot retraction/ drying out
stages of hemostasis
vessel spasm forms platelet plug blood coagulation clot retraction clot dissolution
prophylaxis
treatment is used so patient doesnt bleed out during surgery
DIC=
disseminated intravascular coagulation
less than 100K platelets
thrombocytopenia
vitamin K is known to help the
liver
hemophilia
von willebrand disease
vitamin k deficency disorders
coag defects
thrombopoietin is an example of
colony stimulating factor
disseminated intravascular coagulation
overclotting when major bleeding occurs, uses all platelets and later bleeds to death
purpura
bruising for seemingly no reason
hemorrhage
escaped blood from vessel when profuse
beginning of new vessels
angiogenesis
meaning fat
phospholipid
hemophilia traits
deficiency in factor 8 x linked; boys newborn is severe mild if child bruising on feet bottoms and knees when crawling/walking
plasmapheresis is required for
thrombotic thrombocytopenic purpura
thrombocytes =
platelets
disturbed blood flow can come from
nicotine
high cholesterol etc
coag defects include
hemophilia
von willebrand disease
vitamin k deficiency disorders
thrombin is from
prothrombin
blood clot
thrombus
hemostasis
stoppage of blood flow
plasmapheresis
intentional removal of blood by needle for treatment
petechiae
small round clusters of red pinpoints on skin as a result of bleeding
small round clusters of red pinpoints on skin as a result of bleeding
petechiae
hemostasis stage where blood flow reoxygenates and fibrinolysis (by plasminogen)
clot dissolution
thrombocytopenia number
less than 100K platelets
thrombus
blood clot
antiphospholipid antibody syndrome is an issue from
increased clotting factor
thrombopenia
too little platelets
defects of clotting in liver and intestinal absorption; rarely hereditary
coagulation defects
cascade of clotting factors
blood coagulation
von willebrand disease
mild prophylaxis
range is 150K to 400K
thrombocyte range
many blood clots
thrombotic
white blood cells that live in bloodstream lifespan
24 hours
liver disease
malabsorbtion syndromes
vitamin k deficiency disorders
overclotting when major bleeding occurs, uses all platelets and later bleeds to death
disseminated intravascular coagulation
NSAIDS
pain and fever reducers; all but aspirin
deficiency in factor 8
hemophilia
clot dissolution
blood flow reoxygenates and firbinolysis (by plasminogen)
cell without 02 will signal
pain
von willebrand factor
carries coagulation factor 8
needed to form platelet plug
fibrin is from
fibrinogen
self limiting idiopathic autoimmune response to virus
immune thrombocytopenia
platelet plugs that hook onto built up cholesterol leads to
heart attack
thrombotic
many blood clots
vessel spasms help
decrease blood flow; constricts
lifespan is 8-9 days
thrombocytes
thrombocytosis
too many platelets
drug induced thrombocytopenia
antigen/antibody complex that causes platelet destruction
blood coag traits
cascade of clotthing factors
vitamin k required
prothrombin to thrombin
firbinogen to fibrin
mild prophylaxis disease
von willebrand disease
phospholipid means
fat
escaped blood from vessel when profuse
hemorrhage
stasis
stagnant
thrombocytosis
producing too many platelets
intrinsic stages of hemostasis
blood coagulation
clot retraction
clot dissolution
extrinsic stages of hemostasis
vessel spasm
forms platelet plug
ITP =
immune thrombocytopenia
destroys blood clots
fibrinolysis
platelets =
thrombocytes