blood 5; disorders of hemostasis Flashcards

1
Q

vitamin k deficiency disorders include

A

liver disease

malabsorption syndromes

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2
Q

prothrombin turns into

A

thrombin

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3
Q

bruising for seemingly no reason

A

purpura

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4
Q

carries coagulation factor 8

A

von willebrand factor

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5
Q

stoppage of blood flow

A

hemostasis

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6
Q

thrombotic thrombocytopenic purpura

A

bacteria activates thrombosis; runs out of platelets and bleeds under skin (bruise)
plasmapheresis required
potentially fatal

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7
Q

white blood cells that live in tissue lifespan

A

3-5 days

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8
Q

bruising on bottoms of feet while crawling/walking

A

hemophilia

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9
Q

treatment is used so patient doesnt bleed out during surgery

A

prophylaxis

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10
Q

needed to form platelet plug

A

von willebrand factor

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11
Q

fibrinogen turns into

A

fibrin

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12
Q

average thrombocyte lifespan

A

8-9 days

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13
Q

antigen/antibody complex that causes platelet destruction

A

drug induced thrombocytopenia

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14
Q

angiogenesis

A

beginning of new vessels

happens immediately after injury

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15
Q

TTP =

A

thrombotic thrombocytopenic purpura

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16
Q

hypercoagulability can come from

A

increased platelet function

increase clotting factor activity

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17
Q

increased platelets and clotting factor

A

hypercoagulability

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18
Q

in blood coag, __ is required

A

vitamin K

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19
Q

fibrinolysis

A

destroys blood clots

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20
Q

x linked; coag defected

A

hemophilia

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21
Q

clot retraction/ drying out

A

clot restraction

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22
Q

intentional removal of blood by needle treatment

A

plasmapheresis

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23
Q

thrombocyte range

A

150K to 400K

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24
Q

serum is extracted in this stage of hemostasis

A

clot retraction/ drying out

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25
stages of hemostasis
``` vessel spasm forms platelet plug blood coagulation clot retraction clot dissolution ```
26
prophylaxis
treatment is used so patient doesnt bleed out during surgery
27
DIC=
disseminated intravascular coagulation
28
less than 100K platelets
thrombocytopenia
29
vitamin K is known to help the
liver
30
hemophilia von willebrand disease vitamin k deficency disorders
coag defects
31
thrombopoietin is an example of
colony stimulating factor
32
disseminated intravascular coagulation
overclotting when major bleeding occurs, uses all platelets and later bleeds to death
33
purpura
bruising for seemingly no reason
34
hemorrhage
escaped blood from vessel when profuse
35
beginning of new vessels
angiogenesis
36
meaning fat
phospholipid
37
hemophilia traits
``` deficiency in factor 8 x linked; boys newborn is severe mild if child bruising on feet bottoms and knees when crawling/walking ```
38
plasmapheresis is required for
thrombotic thrombocytopenic purpura
39
thrombocytes =
platelets
40
disturbed blood flow can come from
nicotine | high cholesterol etc
41
coag defects include
hemophilia von willebrand disease vitamin k deficiency disorders
42
thrombin is from
prothrombin
43
blood clot
thrombus
44
hemostasis
stoppage of blood flow
45
plasmapheresis
intentional removal of blood by needle for treatment
46
petechiae
small round clusters of red pinpoints on skin as a result of bleeding
47
small round clusters of red pinpoints on skin as a result of bleeding
petechiae
48
hemostasis stage where blood flow reoxygenates and fibrinolysis (by plasminogen)
clot dissolution
49
thrombocytopenia number
less than 100K platelets
50
thrombus
blood clot
51
antiphospholipid antibody syndrome is an issue from
increased clotting factor
52
thrombopenia
too little platelets
53
defects of clotting in liver and intestinal absorption; rarely hereditary
coagulation defects
54
cascade of clotting factors
blood coagulation
55
von willebrand disease
mild prophylaxis
56
range is 150K to 400K
thrombocyte range
57
many blood clots
thrombotic
58
white blood cells that live in bloodstream lifespan
24 hours
59
liver disease | malabsorbtion syndromes
vitamin k deficiency disorders
60
overclotting when major bleeding occurs, uses all platelets and later bleeds to death
disseminated intravascular coagulation
61
NSAIDS
pain and fever reducers; all but aspirin
62
deficiency in factor 8
hemophilia
63
clot dissolution
blood flow reoxygenates and firbinolysis (by plasminogen)
64
cell without 02 will signal
pain
65
von willebrand factor
carries coagulation factor 8 | needed to form platelet plug
66
fibrin is from
fibrinogen
67
self limiting idiopathic autoimmune response to virus
immune thrombocytopenia
68
platelet plugs that hook onto built up cholesterol leads to
heart attack
69
thrombotic
many blood clots
70
vessel spasms help
decrease blood flow; constricts
71
lifespan is 8-9 days
thrombocytes
72
thrombocytosis
too many platelets
73
drug induced thrombocytopenia
antigen/antibody complex that causes platelet destruction
74
blood coag traits
cascade of clotthing factors vitamin k required prothrombin to thrombin firbinogen to fibrin
75
mild prophylaxis disease
von willebrand disease
76
phospholipid means
fat
77
escaped blood from vessel when profuse
hemorrhage
78
stasis
stagnant
79
thrombocytosis
producing too many platelets
80
intrinsic stages of hemostasis
blood coagulation clot retraction clot dissolution
81
extrinsic stages of hemostasis
vessel spasm | forms platelet plug
82
ITP =
immune thrombocytopenia
83
destroys blood clots
fibrinolysis
84
platelets =
thrombocytes