blood 5; disorders of hemostasis Flashcards

1
Q

vitamin k deficiency disorders include

A

liver disease

malabsorption syndromes

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2
Q

prothrombin turns into

A

thrombin

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3
Q

bruising for seemingly no reason

A

purpura

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4
Q

carries coagulation factor 8

A

von willebrand factor

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5
Q

stoppage of blood flow

A

hemostasis

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6
Q

thrombotic thrombocytopenic purpura

A

bacteria activates thrombosis; runs out of platelets and bleeds under skin (bruise)
plasmapheresis required
potentially fatal

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7
Q

white blood cells that live in tissue lifespan

A

3-5 days

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8
Q

bruising on bottoms of feet while crawling/walking

A

hemophilia

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9
Q

treatment is used so patient doesnt bleed out during surgery

A

prophylaxis

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10
Q

needed to form platelet plug

A

von willebrand factor

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11
Q

fibrinogen turns into

A

fibrin

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12
Q

average thrombocyte lifespan

A

8-9 days

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13
Q

antigen/antibody complex that causes platelet destruction

A

drug induced thrombocytopenia

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14
Q

angiogenesis

A

beginning of new vessels

happens immediately after injury

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15
Q

TTP =

A

thrombotic thrombocytopenic purpura

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16
Q

hypercoagulability can come from

A

increased platelet function

increase clotting factor activity

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17
Q

increased platelets and clotting factor

A

hypercoagulability

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18
Q

in blood coag, __ is required

A

vitamin K

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19
Q

fibrinolysis

A

destroys blood clots

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20
Q

x linked; coag defected

A

hemophilia

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21
Q

clot retraction/ drying out

A

clot restraction

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22
Q

intentional removal of blood by needle treatment

A

plasmapheresis

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23
Q

thrombocyte range

A

150K to 400K

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24
Q

serum is extracted in this stage of hemostasis

A

clot retraction/ drying out

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25
Q

stages of hemostasis

A
vessel spasm
forms platelet plug
blood coagulation
clot retraction
clot dissolution
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26
Q

prophylaxis

A

treatment is used so patient doesnt bleed out during surgery

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27
Q

DIC=

A

disseminated intravascular coagulation

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28
Q

less than 100K platelets

A

thrombocytopenia

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29
Q

vitamin K is known to help the

A

liver

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30
Q

hemophilia
von willebrand disease
vitamin k deficency disorders

A

coag defects

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31
Q

thrombopoietin is an example of

A

colony stimulating factor

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32
Q

disseminated intravascular coagulation

A

overclotting when major bleeding occurs, uses all platelets and later bleeds to death

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33
Q

purpura

A

bruising for seemingly no reason

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34
Q

hemorrhage

A

escaped blood from vessel when profuse

35
Q

beginning of new vessels

A

angiogenesis

36
Q

meaning fat

A

phospholipid

37
Q

hemophilia traits

A
deficiency in factor 8
x linked; boys
newborn is severe
mild if child
bruising on feet bottoms and knees when crawling/walking
38
Q

plasmapheresis is required for

A

thrombotic thrombocytopenic purpura

39
Q

thrombocytes =

A

platelets

40
Q

disturbed blood flow can come from

A

nicotine

high cholesterol etc

41
Q

coag defects include

A

hemophilia
von willebrand disease
vitamin k deficiency disorders

42
Q

thrombin is from

A

prothrombin

43
Q

blood clot

A

thrombus

44
Q

hemostasis

A

stoppage of blood flow

45
Q

plasmapheresis

A

intentional removal of blood by needle for treatment

46
Q

petechiae

A

small round clusters of red pinpoints on skin as a result of bleeding

47
Q

small round clusters of red pinpoints on skin as a result of bleeding

A

petechiae

48
Q

hemostasis stage where blood flow reoxygenates and fibrinolysis (by plasminogen)

A

clot dissolution

49
Q

thrombocytopenia number

A

less than 100K platelets

50
Q

thrombus

A

blood clot

51
Q

antiphospholipid antibody syndrome is an issue from

A

increased clotting factor

52
Q

thrombopenia

A

too little platelets

53
Q

defects of clotting in liver and intestinal absorption; rarely hereditary

A

coagulation defects

54
Q

cascade of clotting factors

A

blood coagulation

55
Q

von willebrand disease

A

mild prophylaxis

56
Q

range is 150K to 400K

A

thrombocyte range

57
Q

many blood clots

A

thrombotic

58
Q

white blood cells that live in bloodstream lifespan

A

24 hours

59
Q

liver disease

malabsorbtion syndromes

A

vitamin k deficiency disorders

60
Q

overclotting when major bleeding occurs, uses all platelets and later bleeds to death

A

disseminated intravascular coagulation

61
Q

NSAIDS

A

pain and fever reducers; all but aspirin

62
Q

deficiency in factor 8

A

hemophilia

63
Q

clot dissolution

A

blood flow reoxygenates and firbinolysis (by plasminogen)

64
Q

cell without 02 will signal

A

pain

65
Q

von willebrand factor

A

carries coagulation factor 8

needed to form platelet plug

66
Q

fibrin is from

A

fibrinogen

67
Q

self limiting idiopathic autoimmune response to virus

A

immune thrombocytopenia

68
Q

platelet plugs that hook onto built up cholesterol leads to

A

heart attack

69
Q

thrombotic

A

many blood clots

70
Q

vessel spasms help

A

decrease blood flow; constricts

71
Q

lifespan is 8-9 days

A

thrombocytes

72
Q

thrombocytosis

A

too many platelets

73
Q

drug induced thrombocytopenia

A

antigen/antibody complex that causes platelet destruction

74
Q

blood coag traits

A

cascade of clotthing factors
vitamin k required
prothrombin to thrombin
firbinogen to fibrin

75
Q

mild prophylaxis disease

A

von willebrand disease

76
Q

phospholipid means

A

fat

77
Q

escaped blood from vessel when profuse

A

hemorrhage

78
Q

stasis

A

stagnant

79
Q

thrombocytosis

A

producing too many platelets

80
Q

intrinsic stages of hemostasis

A

blood coagulation
clot retraction
clot dissolution

81
Q

extrinsic stages of hemostasis

A

vessel spasm

forms platelet plug

82
Q

ITP =

A

immune thrombocytopenia

83
Q

destroys blood clots

A

fibrinolysis

84
Q

platelets =

A

thrombocytes