Blood 2; disorders and leukemia Flashcards
acquired neutropenia can come from
autoimmune issues
infection
induced from drugs
malignant lymphomas
decrease immune response, solid tumor; asymmetrical painless node
lack of rbc and platelets lead to
fatigue
random bruising
bleeding while brushing teeth from lack of platlets
asymptomatic
more fully differentiated cells
insidious
chronic leukemias
leading cause of death in children 1-14
acute leukemia
abnormal B and T cells in lymphs
non-hodgkin lymphoma
infectious mononucleosis is an example of a
lymphoproliferative disorder
achy bones is a symptom of
white blood cell production
necessary for transplants
agranulocytosis
fever at night
tumor necrosis factor
acute myelocytic leukemia info
affects 50 year olds but sometimes children
translocation of chromosome 15 to 17
more chromosome abnormalities are found in those with extra chromosomes (trisomy 21)
IgM converts to
IgG in 2-3 months
meaning gradual but with harmful affects
insidious
wbc higher than 100K
leukocytosis
also known as mono or kissing disease
infectious mononucleosis
chronic leukemias traits
asymptomatic
more fully differentiated cells
insidious
CML=
chronic myelogenous leukemia
types of malignant lymphomas
non-hodgkin
hodgkin
HL =
hodgkin reed sternberg cell
non-hodgkin and hodgkin are types of
malignant lymphomas
meaning the probable course of disease
prognosis
mostly pre-b cell origin
acute lymphocytic leukemia
epstein barr virus causes
infectious mononucleosis
rapid increase in number
proliferation
majority survive more than ten years after diagnosis
chronic lymphocytic leukemia
reed sternberg cell is not found
non-hodgkin lymphoma
cachetin
weight loss from muscle wasting
EBV =
epstein barr virus
asymptomatic
symptoms
blasts
make up the
triphasil phases
chronic myelogenous leukemia traits
starts with BCR-ABL oncogene
triphasil - poor survival of less than 5 years
average is 67 years
stem cell transplant is only cure
affects 50 year olds but occassionally children
acute myelocytic leukemia
malignant neoplasm in blood forming organs; rapid proliferation of abnormal and immature wbc
acute leukemia
in white blood cell count increases, these decrease
red blood cells and platelets
acute means
fast acting
we have a fixed amount of
stem cells
IgM can be tested after
1 week
non-hodgkin lymphoma traits
rapid metastasis reed sternberg cell not found abnormal B and T cells in lymphs H pylori infection in digestive tract found in africa and japan
proliferation
rapid increase in number
triphasil phases
asymptomatic
symptoms
blasts
agranulocytosis is necessary for
transplants
traditional virus (days)
day 1 and 2 are fine
day 3 is ass (neutropenia)
day 4 is fine
leukopenia
abnormally low WBC
85% cure rate to kill cell
hodgkin reed sternberg cell
multiple myelomas
plasma cell dyscrasia
more chromosome abnormalities are found in
those with extra chromosomes (like trisomy 21)
epstein barr virus
hepatitis
hepatosplenomegaly
are all
infectious mononucleosis
decrease in red blood cell and platelets comes from an increase of
white blood cells
live 24 hours
white blood cells
neutropenia
reduced formation of stem cells
for NHL and HL, node swelling is
above the diaphragm
hepatosplenogaly info
enlargement of spleen and liver
running and jostling is no good
splenic rupture when enlarged kills in two hours
cancer moving from primary spot
metastasis
weight loss from muscle wasting
cachetin
for NHL and HL, pain starts
by stage 3 or 4
agranulocytosis
utmost lack of white blood cells
white blood cell lifespan
24 hours
H pylori infection in digestive tract
non-hodgkin lymphoma
fatigue
random bruising
bleeding while brushing teeth
lack of rbc and platelets
triphasil leads to
poor survival
causes most infectious mononucleosis
epstein barr virus
needs to be digested by liver to lower virus count
mono in epstein barr virus
tumor necrosis factor
fever at night
meaning shows no symptoms
asymptomatic
autoimmune issues
infection
or drugs can cause
acquired neutropenia
cancer of the plasma cells in older adults
multiple myelomas
leukocytosis
wbc higher than 100K
AML=
acute myelocytic leukemia
insidious
gradual but with harmful affects
infectious mononucelosis includes
epstein barr virus
hepatitis
hepatosplenomegaly
metastasis
cancer moving from primary spot
chronic lymphocytic leukemia
build up of b lymphocytes in bone marrow, lymph nodes, and blood
infectious mononucleosis is also known as
mono or kissing disease
found in africa and japan
non-hodgkin lymphoma
acquired means
from the first day of life
NHL =
non-hodgkin lymphoma
BCR-ABL oncogene starts
chronic myelogenous leukemia
enlargement of spleen and liver
hepatosplenomegaly
neoplastic disorders of hematopietic and lymphoid origin include
leukemias
malignant lymphomas
plasma cell dyscrasia
only known cure is stem cell transplant
chronic myelogenous leukemia
inflammation of the liver
hepatitis
results in the build up in B lymphocytes in bone marrow, lymph nodes and blood
chronic lymphocytic leukemia
messes up cardiovascular, liver, and spleen enlargement
mono in epstein barr virus
oncogene
beginning of a cancer cell
abnormally low WBC
leukopenia
acute leukemia definition
malignant neoplasm in blood forming organs, rapid proliferation of abnormal and immature wbc
hepatitis
inflammation of the liver
utmost lack of white blood cells
agranulocytosis
decrease immune response, solid tumor; asymmetrical painless node
malignant lymphomas
NHL has a higher death rate because
it mutates and is connected to bacterial and viral infections
chronic means
prolonged course
can be tested after 1 week
IgM
IgM converts to IgG in
2-3 months
B cell mutation in single lymphnode
hodgkin reed sternberg
hodgkins reed sternberg traits
b cell mutation in single node
85% cure rate to kill cell
15-40 years then after 55
ALL=
acute lymphocytic leukemia
meaning from the first day of life
acquired
HSM =
hepatoplenomegaly
chronic lymphocytic leukemia traits
diagnosed in 50-70 yo males
average of 72 years
majority survive more than ten years after diagnosis
symptoms include fatigue and mono within 3 weeks
epstein barr virus
reduced formation of stem cells
neutropenia
yellowing anywhere, especially the eyes, is a sign of
liver failure
symptoms include fatigue
within 3 weeks feels like mono
epstein barr virus
multiple myeloma triats
after 60, average 71 bone pain is first symptom insidious poor prognosis most people dont live past 3 years of diagnosis
asymptomatic
showing no symptoms
kinds of acute leukemia
acute lymphocytic leukemia
acute myelocytic leukemia
example of lymphoproliferative disorder
infectious mononucleosis
acute lymphocytic leukemia info
affects 2-4 year olds
learns from abnormal DNA info
mostly pre-b cell origin
translocation of chromosome 15 to 17
acute myelocytic leukemia
acute leukemia info
keukocytosis
symptom of achy bones, fatigue, night sweats, weight loss, bleeding
exposure to radiation from powerlines at school may be related
leading cause of death in children 1-14
tell tale sign that something is wrong with the liver
yellowing anywhere, especially the eyes
number one symptom from white blood cell production
achy bones, legs an hips in particular
types of leukemias
acute and chronic
only known cure for chronic myelogenous leukemia
stem cell transplant
beginning of a cancer cell
oncogene
CLL
chronic lymphocytic leukemia
converts to IgG
IgM
epstein barr virus info
testing looks for antibodies instead of virus itself
symptoms include fatigue and mono within 3 weeks
mono messes up cardiovasular, liver, and spleen enlargement
mono needs to be digested by liver to lower count
starts chronic myelogenous leukemia
BCR-ABL oncogene
hepatosplenogaly
enlargement of spleen and liver
diagnosed in 50-70 yo males
chronic lymphocytic leukemia
affects 2-4 year olds
acute lymphocytic leukemia
prognosis
the probable course of disease