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PATHO FUCKING AGAIN > Blood 2; disorders and leukemia > Flashcards

Blood 2; disorders and leukemia Flashcards

1
Q

acquired neutropenia can come from

A

autoimmune issues
infection
induced from drugs

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2
Q

malignant lymphomas

A

decrease immune response, solid tumor; asymmetrical painless node

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3
Q

lack of rbc and platelets lead to

A

fatigue
random bruising
bleeding while brushing teeth from lack of platlets

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4
Q

asymptomatic
more fully differentiated cells
insidious

A

chronic leukemias

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5
Q

leading cause of death in children 1-14

A

acute leukemia

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6
Q

abnormal B and T cells in lymphs

A

non-hodgkin lymphoma

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7
Q

infectious mononucleosis is an example of a

A

lymphoproliferative disorder

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8
Q

achy bones is a symptom of

A

white blood cell production

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9
Q

necessary for transplants

A

agranulocytosis

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10
Q

fever at night

A

tumor necrosis factor

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11
Q

acute myelocytic leukemia info

A

affects 50 year olds but sometimes children
translocation of chromosome 15 to 17
more chromosome abnormalities are found in those with extra chromosomes (trisomy 21)

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12
Q

IgM converts to

A

IgG in 2-3 months

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13
Q

meaning gradual but with harmful affects

A

insidious

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14
Q

wbc higher than 100K

A

leukocytosis

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15
Q

also known as mono or kissing disease

A

infectious mononucleosis

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16
Q

chronic leukemias traits

A

asymptomatic
more fully differentiated cells
insidious

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17
Q

CML=

A

chronic myelogenous leukemia

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18
Q

types of malignant lymphomas

A

non-hodgkin

hodgkin

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19
Q

HL =

A

hodgkin reed sternberg cell

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20
Q

non-hodgkin and hodgkin are types of

A

malignant lymphomas

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21
Q

meaning the probable course of disease

A

prognosis

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22
Q

mostly pre-b cell origin

A

acute lymphocytic leukemia

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23
Q

epstein barr virus causes

A

infectious mononucleosis

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24
Q

rapid increase in number

A

proliferation

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25
Q

majority survive more than ten years after diagnosis

A

chronic lymphocytic leukemia

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26
Q

reed sternberg cell is not found

A

non-hodgkin lymphoma

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27
Q

cachetin

A

weight loss from muscle wasting

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28
Q

EBV =

A

epstein barr virus

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29
Q

asymptomatic
symptoms
blasts
make up the

A

triphasil phases

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30
Q

chronic myelogenous leukemia traits

A

starts with BCR-ABL oncogene
triphasil - poor survival of less than 5 years
average is 67 years
stem cell transplant is only cure

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31
Q

affects 50 year olds but occassionally children

A

acute myelocytic leukemia

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32
Q

malignant neoplasm in blood forming organs; rapid proliferation of abnormal and immature wbc

A

acute leukemia

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33
Q

in white blood cell count increases, these decrease

A

red blood cells and platelets

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34
Q

acute means

A

fast acting

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35
Q

we have a fixed amount of

A

stem cells

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36
Q

IgM can be tested after

A

1 week

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37
Q

non-hodgkin lymphoma traits

A 
rapid metastasis
reed sternberg cell not found
abnormal B and T cells in lymphs
H pylori infection in digestive tract
found in africa and japan
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38
Q

proliferation

A

rapid increase in number

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39
Q

triphasil phases

A

asymptomatic
symptoms
blasts

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40
Q

agranulocytosis is necessary for

A

transplants

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41
Q

traditional virus (days)

A

day 1 and 2 are fine
day 3 is ass (neutropenia)
day 4 is fine

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42
Q

leukopenia

A

abnormally low WBC

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43
Q

85% cure rate to kill cell

A

hodgkin reed sternberg cell

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44
Q

multiple myelomas

A

plasma cell dyscrasia

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45
Q

more chromosome abnormalities are found in

A

those with extra chromosomes (like trisomy 21)

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46
Q

epstein barr virus
hepatitis
hepatosplenomegaly
are all

A

infectious mononucleosis

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47
Q

decrease in red blood cell and platelets comes from an increase of

A

white blood cells

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48
Q

live 24 hours

A

white blood cells

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49
Q

neutropenia

A

reduced formation of stem cells

50
Q

for NHL and HL, node swelling is

A

above the diaphragm

51
Q

hepatosplenogaly info

A

enlargement of spleen and liver
running and jostling is no good
splenic rupture when enlarged kills in two hours

52
Q

cancer moving from primary spot

A

metastasis

53
Q

weight loss from muscle wasting

A

cachetin

54
Q

for NHL and HL, pain starts

A

by stage 3 or 4

55
Q

agranulocytosis

A

utmost lack of white blood cells

56
Q

white blood cell lifespan

A

24 hours

57
Q

H pylori infection in digestive tract

A

non-hodgkin lymphoma

58
Q

fatigue
random bruising
bleeding while brushing teeth

A

lack of rbc and platelets

59
Q

triphasil leads to

A

poor survival

60
Q

causes most infectious mononucleosis

A

epstein barr virus

61
Q

needs to be digested by liver to lower virus count

A

mono in epstein barr virus

62
Q

tumor necrosis factor

A

fever at night

63
Q

meaning shows no symptoms

A

asymptomatic

64
Q

autoimmune issues
infection
or drugs can cause

A

acquired neutropenia

65
Q

cancer of the plasma cells in older adults

A

multiple myelomas

66
Q

leukocytosis

A

wbc higher than 100K

67
Q

AML=

A

acute myelocytic leukemia

68
Q

insidious

A

gradual but with harmful affects

69
Q

infectious mononucelosis includes

A

epstein barr virus
hepatitis
hepatosplenomegaly

70
Q

metastasis

A

cancer moving from primary spot

71
Q

chronic lymphocytic leukemia

A

build up of b lymphocytes in bone marrow, lymph nodes, and blood

72
Q

infectious mononucleosis is also known as

A

mono or kissing disease

73
Q

found in africa and japan

A

non-hodgkin lymphoma

74
Q

acquired means

A

from the first day of life

75
Q

NHL =

A

non-hodgkin lymphoma

76
Q

BCR-ABL oncogene starts

A

chronic myelogenous leukemia

77
Q

enlargement of spleen and liver

A

hepatosplenomegaly

78
Q

neoplastic disorders of hematopietic and lymphoid origin include

A

leukemias
malignant lymphomas
plasma cell dyscrasia

79
Q

only known cure is stem cell transplant

A

chronic myelogenous leukemia

80
Q

inflammation of the liver

A

hepatitis

81
Q

results in the build up in B lymphocytes in bone marrow, lymph nodes and blood

A

chronic lymphocytic leukemia

82
Q

messes up cardiovascular, liver, and spleen enlargement

A

mono in epstein barr virus

83
Q

oncogene

A

beginning of a cancer cell

84
Q

abnormally low WBC

A

leukopenia

85
Q

acute leukemia definition

A

malignant neoplasm in blood forming organs, rapid proliferation of abnormal and immature wbc

86
Q

hepatitis

A

inflammation of the liver

87
Q

utmost lack of white blood cells

A

agranulocytosis

88
Q

decrease immune response, solid tumor; asymmetrical painless node

A

malignant lymphomas

89
Q

NHL has a higher death rate because

A

it mutates and is connected to bacterial and viral infections

90
Q

chronic means

A

prolonged course

91
Q

can be tested after 1 week

A

IgM

92
Q

IgM converts to IgG in

A

2-3 months

93
Q

B cell mutation in single lymphnode

A

hodgkin reed sternberg

94
Q

hodgkins reed sternberg traits

A

b cell mutation in single node
85% cure rate to kill cell
15-40 years then after 55

95
Q

ALL=

A

acute lymphocytic leukemia

96
Q

meaning from the first day of life

A

acquired

97
Q

HSM =

A

hepatoplenomegaly

98
Q

chronic lymphocytic leukemia traits

A

diagnosed in 50-70 yo males
average of 72 years
majority survive more than ten years after diagnosis

99
Q

symptoms include fatigue and mono within 3 weeks

A

epstein barr virus

100
Q

reduced formation of stem cells

A

neutropenia

101
Q

yellowing anywhere, especially the eyes, is a sign of

A

liver failure

102
Q

symptoms include fatigue

within 3 weeks feels like mono

A

epstein barr virus

103
Q

multiple myeloma triats

A 
after 60, average 71
bone pain is first symptom
insidious
poor prognosis
most people dont live past 3 years of diagnosis
104
Q

asymptomatic

A

showing no symptoms

105
Q

kinds of acute leukemia

A

acute lymphocytic leukemia

acute myelocytic leukemia

106
Q

example of lymphoproliferative disorder

A

infectious mononucleosis

107
Q

acute lymphocytic leukemia info

A

affects 2-4 year olds
learns from abnormal DNA info
mostly pre-b cell origin

108
Q

translocation of chromosome 15 to 17

A

acute myelocytic leukemia

109
Q

acute leukemia info

A

keukocytosis
symptom of achy bones, fatigue, night sweats, weight loss, bleeding
exposure to radiation from powerlines at school may be related
leading cause of death in children 1-14

110
Q

tell tale sign that something is wrong with the liver

A

yellowing anywhere, especially the eyes

111
Q

number one symptom from white blood cell production

A

achy bones, legs an hips in particular

112
Q

types of leukemias

A

acute and chronic

113
Q

only known cure for chronic myelogenous leukemia

A

stem cell transplant

114
Q

beginning of a cancer cell

A

oncogene

115
Q

CLL

A

chronic lymphocytic leukemia

116
Q

converts to IgG

A

IgM

117
Q

epstein barr virus info

A

testing looks for antibodies instead of virus itself
symptoms include fatigue and mono within 3 weeks
mono messes up cardiovasular, liver, and spleen enlargement
mono needs to be digested by liver to lower count

118
Q

starts chronic myelogenous leukemia

A

BCR-ABL oncogene

119
Q

hepatosplenogaly

A

enlargement of spleen and liver

120
Q

diagnosed in 50-70 yo males

A

chronic lymphocytic leukemia

121
Q

affects 2-4 year olds

A

acute lymphocytic leukemia

122
Q

prognosis

A

the probable course of disease

PATHO FUCKING AGAIN (34 decks)

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