Biological Basis of Mental Disorders Lecture Powerpoint Flashcards
Biopsychiatry
Study that aims to understand mental disorder in terms of biological function (looks at mental illness like a physical illness) as human behavior and thoughts are related to many biological processes
Example of biological basis for depression
An overactive area of the brain - brodmann area 25, is overactive in them
Genetic link in bipolar and schizophrenia
First degree relatives of people with either schizophrenia or bipolar disorder are at increased risk of both these conditions
Infectious disease that can be strongly associated with OCD development
Streptococcal infection
Psychodynamic model of abnormality
Idea that psychological illness comes from repressed emotions and thoughts from experiences in the past, that treatment involves getting patient to admit to what is being repressed
Cognitive model of abnormality
Idea that behavior is the result of abnormal thinking (unhealthy thought processes) through an ABC theory where an activating event, belief withthat event, and a consequence of feeling bad
Behavioral model of abnormality
Idea that regards abnormal actions as learned behavior, behavior not necessarily the thought process (people pay attention to me when I’m drunk so i keep drinking)
Socioeconomic factors associated with mental illness (4)
- Be female
- Divorce
- Live alone
- Single parents
Nature vs nurture
Question of whether certain aspects of behavior are products of genetic or learned influences, ultimately a combination of both (biopsychosocial model)
Personality
Individual difference in pattern of thinking, feeling, and behaving combined determination from genetic temperament and environmental influences
4 personality types (temperament)
-Sanguine (optimistic, active social)
Choleric (short tempered, fast irritable)
Melancholic (analytical wise quiet)
Phlegmatic (relaxed and peaceful)
Neuroplasticity
Ability of the brian to change as a result of one’s experience, brain’s ability to reorganize itself and form new neural connections thru out life. This allows neurons to compensate for injury or disease (CVA, audism, addiction, depression, etc) or develop further and make new connections through psychotherapy and mediation
Kindling
Development of hypersensitivity to a stimulus that initially causes very little response that after repetition produces a full response, the idea that small misfires in the brain in repetition can lead to massive impact (seizure, depression, etc) that sees actual structural changes in neurons occur in response to stimulation leaving an enhanced susceptibility for lifetime persistence
Nuclei of the brain definition
Compact cluster of neurons with specific functions
Basal ganglia
Group of nuclei in the brain that functions in motor behavior and cognitive motivation, attention, and learning, and has been implicated in psychiatric diseases such as anxiety, depression, psychosis, and OCD
Dopamine is elevated in this condition and low in these 3
Schizophrenia, ADHD/fatigue/depression
Norepi is elevated in these 2 conditions and decreased in these 2
Manic episodes and panic attacks, ADHD and depression
Serotonin
Released by the brainstem to help control mood, appetite, and sleep and is implicated in major depression, sleep disorders, and mood disorders
Mesolimbic and mesocortical pathways
Reward dopamine pathways in the brain that carry messages form midbrain to limbic system and cortex, abnormal function is implicated in schizophrenia and addiction
Accumbens nucleus
Nucleus of cells that is a major destination in the mesolimbic pathway that has a close relationship with the ventral tegmental area (VTA), and is the central link in reward system where anything rewarding activates dopamine neurons in the VTA which project into the accumbens nucleus increasing dopamine in this area, majorly linked to addiction promoting desire while decreasing satiety and inhibition
Locus coeruleus
Major adrenergic nucleus in brain that contains norepi producing cells that have an excitatory effect on most of the brain, when stimulated by a lack of drug it drives addiction to do anything necessary to receive stimulation again, involved in panic attacks, PTSD, anxiety, and drug abuse majorly
Amygdala definition
Part of limbic system located in temporal lobe that controls emotional arousal, survival instincts, and memory. When stimulated results in aggression, strongly linked to libido (low T has smaller amygdala) and appears to be linked to BPD, anxiety, and PTSD
Suprachiasmic nucleus
Part of hypothalamus that sits above the optic chiasm and acts as the pacemaker for circadian rhythms implicated in SAD, depression, schizophrenia, etc