Anatomy Ch 4 Test Flashcards
chemical element that shuts down metabolism if present in the body.
arsenic
gradual poisoning from contact with pesticides or environmental pollutants
arsenicosis
how does arsenic damage the body:
binding to bonds between sulfur atoms in proteins
the effects on metabolism largely stem from _____________________________ that helps the breakdown products of glucose enter the _____________
impairment of an enzyme, mitochondria
in the mitochondria, energy is __________ and cells ___________
extracted, run out of energy
exome
the part of the genome that encodes protein
exome is ___ of a genome
1.5%
example of exome:
autism (diagnostic odyssey)
replicating DNA is an __________ process
error-prone
cells can ____ newly replicated DNA, __________, and __ some of them
scan, detect mutations, correct
when DNA repair fails, health suffers with _______ because cells cannot ________, causing ________
cancer, remove it, mutations
when DNA repair fails, health suffers with cancer because cells cannot remove it causing mutations
EFFECTS:
recessive mutation
dominant mutation
recessive mutation:
present in both copies of effected genes to cause symptoms
dominant mutation:
present in only one gene copy
DNA replication is the process of…
making copies of DNA
WHEN does DNA replication happen
S phase of the cell cycle
WHERE does DNA replication happen
nucleus
WHY does DNA replication happen
each new cell produced at the end of the cell cycle has their own complete set of DNA
DNA…
a large molecule in the nucleus of a cell that contains all the genetic information of an organism
DNA is a…
double helix that has to be straightened out because it cannot be copied in double helix
hydrogen bonds help keep ___________
DNA in double helix shape
double helix means…
double stranded or twisted up DNA
DNA is in _______ that each have a _______.
segments, gene
DNA has _________-_____________ genes
20,000-30,000; SPECIFICALLY 20,500
genes are responsible for making specific _________
proteins
each ______ has the information to make _____ its whole life only when it needs to.
gene, one specific thing
when a gene is on it shows a ________
trait
can be turned on and off, can get turned on and off to make a ________
specific protein
we can be carriers of diseases but not reflect that _______
trait
DNA has ________(_______________)
sugar (backbone of DNA)
all information on our body is…
DNA
DNA stands for…
deoxyribose nucleic acid
How long does DNA Replication take
60-90 mins
DNA is copied at ________ times
different
genome:
entire genetic code/DNA strand
DNA is composed of smaller unites called ______________
nucleotides
there are ____ nucleotide pairs in cells
3 billion
the nucleotides in DNA cells contain _____
1 phosphate group, 5 carbon sugar, 4 nitrogen bases
nitrogen bases (amino acids)
adenine
thymine
guanine
cytosine
before DNA can be replicated, it first must _________ from its __________
unzip, double helix shape
5 enzymes that function in the process of DNA replication
helicase
primase
DNA polymerase
exonuclease
DNA ligase
breaks Hydrogen bonds and unzips DNA double helix
helicase
DNA is split into__________
2 individual strands
DNA template
the original strands of DNA that you build the new strand off of
after helicase unzips DNA, the formation is called…
replication fork
enzyme that sequences short RNA called primers
primase
primase binds to…
primer
primer(_____): _____________
RNA - starting point
binds to primer and makes the DNA
DNA polymerase
Primase tells ______ where to start DNA replication
polymerase
exonuclease:
removes primers (RNA) from both strands of DNA
polymerase comes back after________
exonuclease
ligase:
gives up all new segments
ligase ________ the strands
seals up
DNA can only be copied from _________ directions
5’ to 3’
5’ to 3’ determines how each strand of DNA is ___________
replicated
when DNA is made from 5’ to 3’
leading strand
DNA is _________ with ______
one new strand, one old strand
DNA is one new strand with one old strand.
This is called…
semi-conservative
has to be done in segments because of its opposite directions (3’ to 5’)
lagging strand
Lagging strand has to be done in segments because of this opposite directions (3’ to 5’)
what are these segments called?
okazki fragments
replication of lagging strand in segments from 5’ to 3’ and on a 3’ to 5’ strand
okaski fragments
complementary strand
wherever there’s an A, T, and a G, C
complementary strand is when an _________ is being __________
old strand, made with new
RNA:
much smaller molecule and contains the information of a single gene
RNA is a __________ molecule
single stranded
RNA is composed of smaller units called…
nucleotides
the nucleotides in RNA contain the nitrogen bases…
adenine
uracil
guanine
cytosine
RNA comes in 3 forms, each with a different function…
mRNA
tRNA
rRNA
mRNA
messenger RNA
tRNA
transfer RNA
rRNA
ribosomal RNA
RNA stands for
ribonucleic acid
DNA is ________ and RNA is ________
double stranded, single stranded
the strands of DNA are composed of the sugar _____________ but in RNA the strands are composed of the sugar ________
deoxyribose, ribose
DNA contains…
RNA contains…
all genetic info
info from only one gene on the DNA
the process of synthesizing proteins from information in the genes on your DNA
protein synthesis
Protein synthesis takes _______ from ___ to make _______ to make _______.
info, DNA, mRNA, proteins
proteins are different________
lengths
protein synthesis is the process of…
creating proteins
another word for protein synthesis
gene expression
Proteins are really responsible for your _______
traits
_______ are really responsible for your traits
proteins
no protein made…
no trait
how many proteins are in the body
more than 10,000
2 stages of protein synthesis
transcription and translation
when a gene is turned on it…
produces a protein
when a gene is turned on it produces a protein
this is called…
being expressed
when a gene is expressed, we will make that _________ and display that _______
protein, trait
when a gene is copied, it shows a trait for that gene
gene expression
you only show a trait if…
the gene makes the protein it codes for
your genetic traits are because of _______
proteins being made by genes
making a mRNA strand from a gene on the DNA in the nucleus
transcription
synthesizing a protein from info on the mRNA at the ribosome with the help of tRNA and rRNA
translation
transcription happens in the…
nucleus
translation happens in the…
ribosomes in the cytoplasm
WHY does protein synthesis happen?
to make proteins: they get old, have to make new, have to grow to do reactions and fight diseases
WHEN does protein synthesis happen?
ALL THE TIME: interphase
in transcription, __________ is being made from a _________ on the DNA
mRNA, single gene
___________ breaks the H+ bonds between nucleotides to unzip the DNA
RNA polymerase
the RNA polymerase uncoils a _____ and only ______ is copied
little section, one side
Now, a new ________ is made by _______
mRNA strand, RNA polymerase
mRNA contains codes, which are…
instructions to assemble a specific protein
when mRNA is made, DNA…
winds back into double helix shape
Translation:
transfer of amino acids
translation: the mRNA _______ to _______
swam, ribosomes
the mRNA attach to a part made of _______
rRNA
mRNA leaves the ________ and binds to a ______ in the _______
nucleus, ribosome, cytoplams
mRNA builds a chain of _____ that make ________
amino acids, proteins
codon:
code for amino acid
first codon ____ is read by __________
AUG, tRNA’s, anticodon